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Mutational landscape of combined hepatocellular carcinoma and cholangiocarcin...

Sasaki(Motoko),Sato(Yasunori),Nakanuma(Yas... Histopathology 0000-00-00

...KRAS, IDH1 or IDH2 (IDH1/2), ARID1A, the TERT promoter, and TP53, and their relationships with clinicopathological featu...

The possible roles of B-cell novel protein-1 (BCNP1) in cellular signalling p...

Patel(Sapan J),Trivedi(Gaurang L),Darie(Co... J Cell Mol Med 0000-00-00

...KRAS (Kirsten rat sarcoma viral oncogene homolog) and AKT2 (V-Akt Murine Thymoma Viral Oncogene Homolog 2). We also foun...

XPO1-dependent nuclear export is a druggable vulnerability in KRAS-mutant lun...

Kim(Jimi),McMillan(Elizabeth),Kim(Hyun Seo... Nature 0000-00-00

...KRAS proteins in many of the most lethal human cancers, together with the ease of detecting somatic KRAS mutant alleles ...

Radiosensitivity of Colon and Rectal Lung Oligometastasis Treated With Stereo...

Kinj(Rémy),Bondiau(Pierre-Yves),François(E... Clin Colorectal Cancer 0000-00-00

...KRAS mutations (73.3% vs. 40.4%; P = .02). KRAS mutation did not predict for local control, but predicted for a 1-year m...

Regorafenib Versus Trifluridine/Tipiracil for Refractory Metastatic Colorecta...

Masuishi(Toshiki),Taniguchi(Hiroya),Hamauc... Clin Colorectal Cancer 0000-00-00

...KRAS exon 2 wild-type), and no previous treatment with regorafenib or TAS-102.,A total of 146 and 54 patients received r...

Inhibition of RAF1 kinase activity restores apicobasal polarity and impairs t...

Borovski(Tijana),Vellinga(Thomas T),Laouki... Gut 0000-00-00

...KRAS (∼40%). Here we investigated the role of RAF1 in CRC, as a potential, novel target.,Colonosphere cultures were esta...

High selective pressure for Notch1 mutations that induce Myc in T-cell acute ...

Chiang(Mark Y),Wang(Qing),Gormley(Anna C),... Blood 0000-00-00

...Kras mice transduced with Myc developed T-ALLs that were GSI-insensitive and lacked Notch1 mutations. In contrast, Kras ...

Identification of Stem Cells in the Epithelium of the Stomach Corpus and Antr...

Matsuo(Junichi),Kimura(Shunichi),Yamamura(... Gastroenterology 0000-00-00

...KrasG12D/+ mice; gastric tissues were collected and analyzed by histology and immunofluorescence.,Most proliferation occ...

Assessment of DDR2, BRAF, EGFR and KRAS mutations as therapeutic targets in n...

Yashima(Hideaki),Shimizu(Kimihiro),Araki(T... Mol Clin Oncol 0000-00-00

...KRAS codon 12 mutations were also found in 3 SCC patients and 1 large-cell neuroendocrine carcinoma patient. EGFR and KR...

Mutations in MicroRNA Genes and Their Binding Sites are Infrequently Associat...

Maqbool(Raihana),Ismail(Rehana),Hussain(Ma... Microrna 0000-00-00

...KRAS, TP53 and GJA1 3'UTR. This study was carried out on 60 human colorectal cancer tissue samples. Our sequencing resul...

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