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A novel approach for predicting P-glycoprotein (ABCB1) inhibition using molecul…

Broccatelli(F),Carosati(E),Neri(A),Frosini(M… J Med Chem 2011-03-24

...Pgp can be used to overcome multidrug resistance. Given this dual purpose, reliable in silico procedures to predict Pgp ...

Effect of peach gum polysaccharide on the rheological and 3D printing propertie…

Zhou(L),Meng(FB),Li(YC),Shi(XD),Yang(YW),Wan… Int J Biol Macromol 2023-12-31

...PGP) was added to gelatin to prepare a 3D-printed functional gummy candy encapsulating curcumin. Rheology tests indicate...

Isolation and identification of the bitter compound from Huangjiu.

Lu(Z),Xie(G),Wu(D),Yang(L),Jin(Z),Hu(Z),Xu(X… Food Chem 2021-07-01

...PGP) was successfully identified from Huangjiu for the first time. Quantitative analysis showed that PGP contents ranged...

Novel curcumin derivatives as P-glycoprotein inhibitors: Molecular modeling, sy…

Sagnou(M),Novikov(FN),Ivanova(ES),Alexiou(P)… Eur J Med Chem 2020-07-15

...Pgp mediated efflux and sensitization of multidrug resistant (MDR) cells to the Pgp transported drug doxorubicin (Dox). ...

The neuronal marker protein gene product 9.5 (PGP 9.5) is phenotypically expres…

Schumacher(U),Mitchell(BS),Kaiserling(E) DNA Cell Biol 1994-08-00

...PGP 9.5) in nonneuroendocrine tissues of the human breast. Using antibodies directed against PGP 9.5 in an immunohistolo...

Alterations in Ca2+ transport ATPase and P-glycoprotein expression can mediate …

Gutheil(JC),Hart(SR),Belani(CP),Melera(PW),H… J Biol Chem 1994-03-18

...pgp1 cDNA, and reversal of TG resistance with known inhibitors of pgp function. However, pgp is unlikely to represent th...

Classical and novel forms of multidrug resistance and the physiological functio…

Borst(P),Schinkel(AH),Smit(JJ),Wagenaar(E),V… Pharmacol Ther 1993-11-00

...Pgp) genes. The mutations do not interfere with viability or fertility, showing that these Pgps have no indispensable ro...

Cyclosporin A inhibits calcineurin (phosphatase 2B) and P-glycoprotein activity…

Carrero(JC),Lugo(H),Pérez(DG),Ortiz-Martínez… Int J Parasitol 2004-08-00

...Pgp activity. This suggestion was confirmed by results from experiments of Pgp-dependent effux of rhodamine from pre-loa...

Cyclosporine A enables vincristine-induced apoptosis during reversal of multid…

de Souza(PS),da Cunha Vasconcelos(F),Silva(L… Tumour Biol 2012-08-00

...Pgp activity by using CsA did not induce cytotoxic effects in leukemia cells, independently of Pgp expression. However, ...

Protein kinase C-independent correlation between P-glycoprotein expression and …

Miwa(A),Ueda(K),Okada(Y) J Membr Biol 1997-05-01

...PGP expression. Patch-clamp whole-cell recordings showed that osmotic swelling activates Cl- currents not only in PGP-ex...

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