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Increasing incidence of differentiated thyroid cancer in the United States, 1...

Chen(Amy Y),Jemal(Ahmedin),Ward(Elizabeth ... Cancer 2009-09-17

...APC, 3.7) and women (1988-2005: APC, 5.70) and for distant SEER stage disease among men (APC, 3.7) and women (APC, 2.3)....

T cell receptor signaling induced by an analog peptide of type II collagen re...

Tang(Bo),Zhou(Jing),Park(Jeoung-Eun),Culli... Clin Immunol 2009-10-08

...APCs pulsed with A9 failed to induce T cell phosphorylation of TCR-zeta and ZAP-70, we explored alternative signaling pa...

Establishment and characterization of a cancer cell line derived from an aggr...

Chen(Tina T-L),Rakheja(Dinesh),Hung(Jaclyn... Pediatr Blood Cancer 2009-10-13

...APC, MYH, MLH1, or MSH2 genes.,This cell line, Hep293TT, is a valuable resource for the study of childhood liver cancer ...

Ca(2+) regulates the subcellular localization of adenomatous polyposis coli t...

Togo(Tatsuru) Biochem Biophys Res Commun 2009-09-21

...APC) following an increase in [Ca(2+)](i) was observed using Xenopus A6 epithelial cell expressing GFP-tagged APC. An in...

The COP9 signalosome mediates beta-catenin degradation by deneddylation and b...

Huang(Xiaohua),Langelotz(Corinna),Hetfeld-... J Mol Biol 2009-08-24

...APC via CSN-associated USP15. The CSN regulates the balance between beta-catenin and APC. Disturbance of this balance ca...

Structure of a prokaryotic virtual proton pump at 3.2 A resolution.

Fang(Yiling),Jayaram(Hariharan),Shane(Tani... Nature 2009-09-23

...APC superfamily of membrane proteins, which transports amino acids, polyamines and organic cations in a multitude of bio...

A targeted constitutive mutation in the APC tumor suppressor gene underlies m...

Gaspar(Claudia),Franken(Patrick),Molenaar(... PLoS Genet 2009-10-13

...Apc1572T, obtained by targeting a truncated mutation at codon 1572 in the endogenous Apc gene. This hypomorphic mutant a...

Chromosomally and microsatellite stable colorectal carcinomas without the CpG...

Ostwald(Christiane),Linnebacher(Michael),W... Int J Oncol 2009-09-01

...APC, and p53. Morphology was reviewed, and nuclear beta-catenin translocation was assessed by immunohistochemistry. Base...

Molecular pathogenesis of endometriosis-associated clear cell carcinoma of th...

Kobayashi(Hiroshi),Kajiwara(Hirotaka),Kana... Oncol Rep 2009-09-14

...APC (early event), p53, polo-like kinases, Emi1 and K-RAS (late event) genes may be involved in CCC carcinogenesis. The ...

Endogenous expression of the sodium iodide symporter mediates uptake of iodid...

Gaertner(Florian C),Rohde(Franziska),Muell... Int J Cancer 2009-12-02

...APC) were screened for NIS expression by RT-PCR. In vitro, functional NIS activity was detected in murine CMT93 rectal c...

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