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The immunosuppressive properties of the HIV Vpr protein are linked to a singl...

Tcherepanova(Irina),Starr(Aijing),Lackford... PLoS One 2009-11-17

...APCs) is suppressed by Vpr, implicating it as an important virulence factor. We hypothesize that Vpr protein packaged in...

[Cellular and molecular deregulations driving the metastatic phenotype].

Zeitoun(Guy) Med Sci (Paris) 2009-07-28

...APC mutations that deregulates the WNT pathway. Position of the mutations within the coding sequence are essential for t...

Activated protein C protects against ventilator-induced pulmonary capillary l...

Finigan(James H),Boueiz(Adel),Wilkinson(Em... Am J Physiol Lung Cell Mol ... 2009-07-16

...APC or vehicle via jugular vein 1 h before MV. In separate experiments, mice were ventilated for 4 h and received APC 30...

The effect of disease-associated HRPT2 mutations on splicing.

Hahn(Michael A),McDonnell(Julie),Marsh(Deb... J Endocrinol 2009-07-30

...APC and MLH1. Given that the effect of HRPT2 mutations on splicing has not been widely studied, we used an in vitro spli...

Immunization with radiation-attenuated Plasmodium berghei sporozoites induces...

Jobe(Ousman),Donofrio(Gina),Sun(Guangping)... PLoS One 2009-05-29

...APC) that activate these CD8+ T(EM) cells nor the site of their induction have been fully investigated. Because conventi...

The DC-HIL/syndecan-4 pathway inhibits human allogeneic T-cell responses.

Chung(Jin-Sung),Bonkobara(Makoto),Tomihari... Eur J Immunol 2009-05-08

...APC to corresponding receptors on T cells. In mice, we discovered that binding of DC-HIL on APC to syndecan-4 (SD-4) on ...

An in vivo study of Cdh1/APC in breast cancer formation.

Fujita(Takeo),Liu(Weijun),Doihara(Hiroyosh... Int J Cancer 2009-08-04

...APC in regulating tumor formation via governing the Skp2-p27-cyclinE/CDK2 axis. In this work, we used a xenograft mouse ...

Enhanced genomic instabilities caused by deregulated microtubule dynamics and...

Rao(Chinthalapally V),Yamada(Hiroshi Y),Ya... Carcinogenesis 2009-09-15

...Apc/Apc) in genomic stability and suppression of tumor development, with a focus on information from genetically enginee...

Activated protein C protects against myocardial ischemia/ reperfusion injury ...

Loubele(Sarah T B G),Spek(C Arnold),Leende... Arterioscler Thromb Vasc Bi... 2009-07-15

...APC was administered in an animal model for myocardial I/R. APC largely inhibited early myocardial I/R injury after vary...

Protective response to Leishmania major in BALB/c mice requires antigen proce...

Kamala(Tirumalai),Nanda(Navreet K) J Immunol 2009-04-23

...APC, and 2) focus the display of epitopes by APC to the immunodominant ones. We tested the hypothesis that deficiency of...

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