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Cyclooxygenase-2 inhibitors down-regulate osteopontin and Nr4A2-new therapeut...

Zagani(Rachid),Hamzaoui(Nadim),Cacheux(Wul... Gastroenterology 2009-10-15

...Apc(Delta14/+) mice to identify genes that respond to these drugs.,Apc(Delta14/+) mice were given a single daily injecti...

Cyclin A/cdk2 regulates adenomatous polyposis coli-dependent mitotic spindle ...

Beamish(Heather),de Boer(Leonore),Giles(Ni... J Biol Chem 2009-11-24

...APC in late G2 phase and phosphorylates it at Ser-1360, located in the mutation cluster region of APC. Mutation of APC S...

Role of the renin-angiotensin system in autoimmune inflammation of the centra...

Stegbauer(Johannes),Lee(De-Hyung),Seubert(... Proc Natl Acad Sci U S A 2009-11-06

...APC). Treatment with the renin inhibitor aliskiren, the angiotensin II converting-enzyme inhibitor enalapril, as well as...

The APC Variant p.Glu1317Gln predisposes to colorectal adenomas by a novel me...

Dallosso(Anthony R),Jones(Siân),Azzopardi(... Hum Mutat 2009-12-15

Multiple rare nonsynonymous variants in APC predispose to colorectal adenomas. The mechanisms through which such variant...

Short-term administration of ethanol in mice deviates antigen presentation ac...

Andrade(M C),Albernaz(M J S),Araújo(M S S)... Scand J Immunol 2009-09-21

...APC populations, downregulating splenic macrophages and DC activity but up-regulating B lymphocyte function as APC, and ...

Nup358 interacts with APC and plays a role in cell polarization.

Murawala(Prayag),Tripathi(Mukesh Mani),Vya... J Cell Sci 2009-12-21

...APC. Through the same region, APC interacts with Nup358 (also called RanBP2), a microtubule-binding nucleoporin. Ectopic...

Superantigen-activated regulatory T cells inhibit the migration of innate imm...

Tanriver(Yakup),Martín-Fontecha(Alfonso),R... J Immunol 2009-09-18

...APC coexpressing OVA and the superantigen were injected. These data suggest that the preactivation of regulatory T cells...

The multi-functionality of CD40L and its receptor CD40 in atherosclerosis.

Lievens(Dirk),Eijgelaar(Wouter J),Biessen(... Thromb Haemost 2009-10-21

...APC) and to contribute to T-cell priming and B-cell isotype switching. Besides their presence on T-cells and APCs, CD40 ...

Isolation of dendritic cells.

Inaba(Kayo),Swiggard(William J),Steinman(R... Curr Protoc Immunol 2009-10-08

...APC). The first method involves the isolation of DCs from mouse spleen, resulting in a cell population that is highly en...

Insights into anaphase promoting complex TPR subdomain assembly from a CDC26-...

Wang(Jing),Dye(Billy T),Rajashankar(Kanaga... Nat Struct Mol Biol 2009-09-25

...APC6, a core TPR protein required for APC integrity. Notably, CDC26-APC6 association involves an intermolecular TPR mimi...

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