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The polarity protein Par1b/EMK/MARK2 regulates T cell receptor-induced microt...

Lin(Joseph),Hou(Kirk K),Piwnica-Worms(Hele... J Immunol 2009-09-15

Engagement of a T cell to an APC induces the formation of an immunological synapse as well as reorientation of the micro...

The impact of TCR-binding properties and antigen presentation format on T cel...

Chervin(Adam S),Stone(Jennifer D),Holler(P... J Immunol 2009-09-15

...APCs. However, when the pepMHC was immobilized (plate bound), T cells with the lowest affinity TCRs (e.g., K(D) = 30 mic...

Insufficient TLR activation contributes to the slow development of CD8+ T cel...

Padilla(Angel M),Simpson(Laura J),Tarleton... J Immunol 2009-09-15

...APCs can modestly speed the generation of anti-T. cruzi T cell responses. Given these characteristics of the response, w...

Cathepsin S regulates class II MHC processing in human CD4+ HLA-DR+ T cells.

Costantino(Cristina Maria),Ploegh(Hidde L)... J Immunol 2009-09-15

...APC-CD4(+) HLA-DR(+) cells modulate self-Ag presentation as a consequence of activation. Furthermore, cathepsin S expres...

Inhibition of WNT signaling by G protein-coupled receptor (GPCR) kinase 2 (GR...

Wang(Liming),Gesty-Palmer(Diane),Fields(Ti... Mol Endocrinol 2009-11-16

...APC; 2) The GRK2-APC interaction was promoted by GRK2 enzymatic activity; and 3) Deletion of the RGS domain in GRK2 prev...

Biological characteristics of dendritic cells derived from peripheral blood o...

Lan(Chun-Yan),Liu(Ji-Hong),Xia(Jian-Chuan)... Ai Zheng 2009-10-22

...APC) and play a vital role in stimulating human immune response against cancer. At present, most data concerning the imm...

Trends in lung cancer mortality in Portugal (1955-2005).

Alves(Luís),Bastos(Joana),Lunet(Nuno) Rev Port Pneumol 2009-08-25

...APC) in mortality and to identify any inflection points.,Between 1955 and 2005 we observed a stabilisation in lung cance...

The cytoplasmic tail of the T cell receptor CD3 epsilon subunit contains a ph...

Deford-Watts(Laura M),Tassin(Tara C),Becke... J Immunol 2009-09-15

...APCs, and delayed CD3 epsilon localization to the immunological synapse. Overall, these findings demonstrate a functiona...

IFN-gamma attenuates antigen-induced overall immune response in the airway as...

Nakagome(Kazuyuki),Okunishi(Katsuhide),Ima... J Immunol 2009-08-20

...APCs and their migration to regional lymph nodes were also suppressed. These results suggest that the Th1 cytokine IFN-g...

Early life exposure to lipopolysaccharide suppresses experimental autoimmune ...

Ellestad(Kristofor K),Tsutsui(Shigeki),Noo... J Immunol 2009-08-20

...APC from LPS-exposed animals stimulated less T lymphocyte proliferation but increased expansion of CD4(+)FoxP3(+) T cell...

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