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PMID: 10521521 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

A defect in beta-oxidation causes abnormal inflorescence development in Arabidopsis.

The Plant cell ·Vol. 11 ·No. 10 ·1999-10-00 ·Pages 1911-24

Richmond TA, Bleecker AB

Abstract

The abnormal inflorescence meristem1 (aim1) mutation affects inflorescence and floral development in Arabidopsis. After the transition to reproductive growth, the aim1 inflorescence meristem becomes disorganized, producing abnormal floral meristems and resulting in plants with severely reduced fertility. The derived amino acid sequence of AIM1 shows extensive similarity to the cucumber multifunctional protein involved in beta-oxidation of fatty acids, which possesses l-3-hydroxyacyl-CoA hydrolyase, l-3-hydroxyacyl-dehydrogenase, d-3-hydroxyacyl-CoA epimerase, and Delta(3), Delta(2)-enoyl-CoA isomerase activities. A defect in beta-oxidation has been confirmed by demonstrating the resistance of the aim1 mutant to 2,4-diphenoxybutyric acid, which is converted to the herbicide 2,4-D by the beta-oxidation pathway. In addition, the loss of AIM1 alters the fatty acid composition of the mature adult plant.

MeSH Terms
Amino Acid Sequence Arabidopsis/genetics,growth & development,physiology Arabidopsis Proteins Cloning, Molecular DNA, Bacterial Enoyl-CoA Hydratase/metabolism Fatty Acids/metabolism Germination Herbicides/pharmacology Molecular Sequence Data Multienzyme Complexes/chemistry,genetics,metabolism Oxidation-Reduction Plants, Genetically Modified Sequence Homology, Amino Acid
Chemicals
AIM1 protein, Arabidopsis Arabidopsis Proteins DNA, Bacterial Fatty Acids Herbicides Multienzyme Complexes T-DNA Enoyl-CoA Hydratase
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Richmond T A
Department of Botany, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.
Bleecker A B
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Article Info
Journal
The Plant cell
Abbr.
Plant Cell
ISSN
1040-4651
DOI
10.1105/tpc.11.10.1911
Published
1999-10-00
Pages
1911-24
Language
English
Region
England
NLM ID
9208688
PMCID
PMC144112
Subset
IM
Grants
NIA NIH HHS · 5F32AGO5542-02 · United States
NIGMS NIH HHS · GM07133-181 · United States
External Links
PubMed source DOI: 10.1105/tpc.11.10.1911 PMC Full Text View journal details
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