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PMID: 10679003 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Quantitative imaging of pre-mRNA splicing factors in living cells.

Molecular biology of the cell ·Vol. 11 ·No. 2 ·2000-02-00 ·Pages 413-8

Eils R, Gerlich D, Tvaruskó W, Spector DL, Misteli T

Abstract

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MeSH Terms
Animals Biological Transport Cell Line Cell Nucleus/chemistry,genetics,metabolism,ultrastructure Cell Survival Computer Simulation Cricetinae Microscopy, Video/instrumentation,methods Nuclear Proteins/metabolism RNA Precursors/chemistry,genetics,metabolism RNA Splicing/genetics RNA, Messenger/chemistry,genetics,metabolism RNA-Binding Proteins Serine-Arginine Splicing Factors Spliceosomes/chemistry,genetics,metabolism,ultrastructure Time Factors Transcription, Genetic/genetics,physiology
Chemicals
Nuclear Proteins RNA Precursors RNA, Messenger RNA-Binding Proteins Serine-Arginine Splicing Factors
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Eils R
Bioinformatics Group, Interdisciplinary Center of Scientific Computing, University of Heidelberg, 69120 Heidelberg, Germany. [email protected]
Gerlich D
Tvaruskó W
Spector D L
Misteli T
References (13)
13 references, click to expand
  1. Single particle tracking. Analysis of diffusion and flow in two-dimensional systems.
    Biophys J. 1991 Oct;60(4):910-21 PMID: 1742458
  2. In vivo evidence that transcription and splicing are coordinated by a recruiting mechanism.
    Cell. 1993 Apr 9;73(1):47-59 PMID: 8462102
  3. Macromolecular domains within the cell nucleus.
    Annu Rev Cell Biol. 1993;9:265-315 PMID: 8280462
  4. Active and inactive genes localize preferentially in the periphery of chromosome territories.
    J Cell Biol. 1996 Dec;135(5):1195-205 PMID: 8947544
  5. Three-dimensional reconstruction of painted human interphase chromosomes: active and inactive X chromosome territories have similar volumes but differ in shape and surface structure.
    J Cell Biol. 1996 Dec;135(6 Pt 1):1427-40 PMID: 8978813
  6. The dynamics of a pre-mRNA splicing factor in living cells.
    Nature. 1997 May 29;387(6632):523-7 PMID: 9168118
  7. Time-resolved analysis and visualization of dynamic processes in living cells.
    Proc Natl Acad Sci U S A. 1999 Jul 6;96(14):7950-5 PMID: 10393928
  8. Interphase chromosomes undergo constrained diffusional motion in living cells.
    Curr Biol. 1997 Dec 1;7(12):930-9 PMID: 9382846
  9. Structure and function in the nucleus.
    Science. 1998 Apr 24;280(5363):547-53 PMID: 9554838
  10. The cellular organization of gene expression.
    Curr Opin Cell Biol. 1998 Jun;10(3):323-31 PMID: 9640532
  11. Serine phosphorylation of SR proteins is required for their recruitment to sites of transcription in vivo.
    J Cell Biol. 1998 Oct 19;143(2):297-307 PMID: 9786943
  12. RNA polymerase II targets pre-mRNA splicing factors to transcription sites in vivo.
    Mol Cell. 1999 Jun;3(6):697-705 PMID: 10394358
  13. Applications of the green fluorescent protein in cell biology and biotechnology.
    Nat Biotechnol. 1997 Oct;15(10):961-4 PMID: 9335045
Article Info
Journal
Molecular biology of the cell
Abbr.
Mol Biol Cell
ISSN
1059-1524
Published
2000-02-00
Pages
413-8
Language
English
Region
United States
NLM ID
9201390
PMCID
PMC14782
Subset
IM
Grants
NIGMS NIH HHS · R01 GM042694 · United States
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