Abstract
Three Rec- mutants of Haemophilus influenzae have been studied with respect to their transformability, ultraviolet and mitomycin C sensitivities, spontaneous and ultraviolet-induced deoxyribonucleic acid breakdown, inducibility of lysogens, and the linkage of the three mutations to a streptomycin resistance marker. The data indicate that the three mutations cause the same phenotypic changes, and that they are all on the same gene. Transformability of the mutants is different when two different media are used for competence development, although transformability with the two competence methods is not different in a Rec- strain that is mutant at another gene.
MeSH Terms
Chromosome Mapping
DNA, Bacterial/radiation effects
Drug Resistance, Microbial
Genes
Genetic Linkage
Haemophilus influenzae/drug effects,radiation effects
Lysogeny
Mitomycins/pharmacology
Mutation
Radiation Effects
Recombination, Genetic
Streptomycin/pharmacology
Transformation, Genetic
Ultraviolet Rays
Chemicals
DNA, Bacterial
Mitomycins
Streptomycin
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Kooistra J
Setlow J K
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