The possible presence of a bursa-independent, IgM-producing system in chicks.

Immunology ·Vol. 28 ·No. 2 ·1975-02-00 ·Pages 293-9

Sato K, Abe S

Abstract

The number of splenic plaque-forming cells significantly increased in bursectomized chicks immunized secondarily with SRBC. Further experiments using rabbit antiserum specific to the bursa of Fabricius indicate that the different types of antibody-producing cells might be engaged in the synthesis of IgM in bursectomized chicks. The possible presence of a bursa-independent, IgM-producing system in chicks is suggested.

MeSH Terms

Animals Antibody-Producing Cells/immunology Bursa of Fabricius/immunology Cell Survival Chickens Erythrocytes/immunology Hemagglutinins/analysis Hemolytic Plaque Technique Immune Sera/pharmacology Immunity, Cellular Immunization Immunoglobulin M/biosynthesis Immunologic Memory Rabbits/immunology Sheep/immunology Spleen/cytology,immunology

Chemicals

Hemagglutinins Immune Sera Immunoglobulin M

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Sato K

Abe S

References (20)

20 references, click to expand

The influence of dipping eggs in male hormone solutions on lymphatic tissue and antibody response of chickens.
Endocrinology. 1961 Nov;69:984-5 PMID: 13899227
Studies on antilymphocyte antibody in the chicken. II. Effect of rabbit antithymus and antibursa globulin on immune reactions in young chickens.
Clin Exp Immunol. 1970 Nov;7(5):709-22 PMID: 4099669
Normal immune responses of bursaless chickens to a secondary antigenic stimulus.
Nature. 1968 Jan 20;217(5125):231-5 PMID: 4170575
Immune globulin production by the bursa of Fabricius of young chickens.
Immunology. 1968 Jul;15(1):123-34 PMID: 4174144
Development and function of the immunoglobulin producing system. I. Effect of bursectomy at different stages of development on germinal centers, plasma cells, immunoglobulins and antibody production.
Int Arch Allergy Appl Immunol. 1969;35(3):242-52 PMID: 4179663
Immunoglobulins, antibodies and the bursa of Fabricus: induction of agammaglobulinemia and the loss of all antibody-forming capacity by hormonal bursectomy.
J Immunol. 1969 Dec;103(6):1317-30 PMID: 4188336
Appendix and gamma M-antibody formation. I. Immune response and tolerance to bovine gamma globulin in irradiated, appendix-shielded rabbits.
J Immunol. 1970 Mar;104(3):616-25 PMID: 4190968
Production of mercaptoethanol sensitive antibody in bursectomized chicks.
Poult Sci. 1972 Jul;51(4):1358-60 PMID: 4647593
Antibody responses in bursa-deficient chickens.
J Immunol. 1966 Nov;97(5):693-9 PMID: 4959015
Immunocompetent cells of the chicken. I. Specific surface antigenic markers on bursa and thymus cells.
J Exp Med. 1971 Oct 1;134(4):1036-45 PMID: 4938447
Are splenic plaque forming cells sensitive to heat in vitro.
Life Sci. 1970 Feb 8;9(3):175-80 PMID: 4907559
Selective inhibition of plaque-forming cells by bursa-specific antisera.
J Immunol. 1971 May;106(5):1416-7 PMID: 4930073
The functions of the thymus system and the bursa system in the chicken.
J Exp Med. 1966 Jan 1;123(1):75-102 PMID: 5323079
Suppression of immunoglobulin G synthesis as a result of antibody-mediated suppression of immunoglobulin M synthesis in chickens.
Proc Natl Acad Sci U S A. 1970 Dec;67(4):1918-25 PMID: 5275387
Development and distribution of immunoglobulin-containing cells in the chicken. An immunofluorescent analysis using purified antibodies to mu, gamma and light chains.
J Immunol. 1971 Feb;106(2):371-82 PMID: 5101790
Role of the bursa of Fabricius in IgG and IgM production in the chicken: evidence for the role of a non-bursal site in the development of humoral immunity.
J Immunol. 1971 Aug;107(2):493-503 PMID: 5568775
Alterations in the kinetics of hemagglutinin formation following embryonic bursectomy.
J Immunol. 1971 Aug;107(2):512-7 PMID: 5106055
Studies on the lymphocytes in the intestinal epithelium of the chicken. IV. Effect of bursectomy.
Int Arch Allergy Appl Immunol. 1970;39(4):342-51 PMID: 5473641
Antigenic specificities of bursal and thymic lymphocytes in the chicken.
Immunology. 1970 Sep;19(3):465-8 PMID: 5471830
Experimental studies on the development of the bursa of Fabricius.
Dev Biol. 1966 Aug;14(1):40-51 PMID: 5969484

Article Info

Journal

Immunology

Abbr.

Immunology

ISSN

0019-2805

Published

1975-02-00

Pages

293-9

Language

English

Region

England

NLM ID

0374672

PMCID

PMC1445797

Subset

External Links

PubMed source PMC Full Text View journal details

Analysis Services

The possible presence of a bursa-independent, IgM-producing system in chicks.

Contact

WeChat Official Account