In vitro interaction between normal cynolmolgus monkey alveolar macrophages and Legionnaires disease bacteria.

Infection and immunity ·Vol. 25 ·No. 2 ·1979-08-00 ·Pages 761-3

Kishimoto RA, Kastello MD, White JD, Shirey FG, McGann VG, Larson EW, Hedlund KW

Abstract

The interaction between normal cynomolgus monkey alveolar macrophages and Legionnaires disease bacteria was studied by transmission electron microscopy. After ingestion of Legionnaires disease bacteria, the organisms replicated within macrophages and destroyed the phagocytic cell.

MeSH Terms

Animals Disease Models, Animal Female Haplorhini Legionnaires' Disease/immunology,microbiology Macaca fascicularis Macrophages/immunology Male Microscopy, Electron Phagocytosis Pulmonary Alveoli/cytology,immunology,microbiology Rats

Authors & Affiliations

7 authors, click to expand affiliations / ORCID

Kishimoto R A

Kastello M D

White J D

Shirey F G

McGann V G

Larson E W

Hedlund K W

References (8)

8 references, click to expand

Recovery of alveolar macrophages from rhesus and cynomolgus macaques by lung lavage.
Am J Vet Res. 1979 Feb;40(2):271-3 PMID: 111588
Legionnaires' disease: description of an epidemic of pneumonia.
N Engl J Med. 1977 Dec 1;297(22):1189-97 PMID: 335244
Pulmonary alveolar macrophage. Defender against bacterial infection of the lung.
J Clin Invest. 1974 Sep;54(3):519-28 PMID: 4853956
Legionnaires' disease. Pathological and historical aspects of a 'new' disease.
Arch Pathol Lab Med. 1978 Jul;102(7):337-43 PMID: 580865
The pathology of Legionnaires' disease. Fourteen fatal cases from the 1977 outbreak in Vermont.
Arch Pathol Lab Med. 1978 Jul;102(7):344-50 PMID: 580866
The morphology of the Legionnaires' disease organism.
Am J Pathol. 1978 Mar;90(3):701-22 PMID: 629329
Demonstration of the agent of Legionnaires' disease in tissue.
N Engl J Med. 1977 Dec 1;297(22):1218-20 PMID: 72358
Electron microscopic study on the interaction between normal guinea pig peritoneal macrophages and Coxiella burnetii.
Infect Immun. 1976 Oct;14(4):1087-96 PMID: 825466

Article Info

Journal

Infection and immunity

Abbr.

Infect Immun

ISSN

0019-9567

DOI

10.1128/iai.25.2.761-763.1979

Published

1979-08-00

Pages

761-3

Language

English

Region

United States

NLM ID

0246127

PMCID

PMC414508

Subset

External Links

PubMed source DOI: 10.1128/iai.25.2.761-763.1979 PMC Full Text View journal details

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In vitro interaction between normal cynolmolgus monkey alveolar macrophages and Legionnaires disease bacteria.

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