Association of endonuclease activity with serotypes belonging to the three subgroups of human adenoviruses.

Journal of virology ·Vol. 16 ·No. 2 ·1975-08-00 ·Pages 456-8

Marusyk RG, Morgan AR, Wadell G

Abstract

Endonuclease activity has been detected in association with highly purified virions, pentons, and/or dodecons of adenovirus types 2, 3, 5, 9, 12, 15, and 16. Only single-strand scissions in substrate DNA were detected. The nuclease activity was detected by a highly sensitive ethidium bromide fluorimetric assay procedure.

MeSH Terms

Adenoviridae/enzymology Bacteriophages Carcinoma Cell Line DNA Viruses DNA, Circular/metabolism DNA, Viral/metabolism Deoxyribonucleases/metabolism Endonucleases/metabolism Ethidium Fluorometry HeLa Cells Humans Mouth Neoplasms Pseudomonas Serotyping Viral Proteins/metabolism

Chemicals

DNA, Circular DNA, Viral Viral Proteins Deoxyribonucleases Endonucleases Ethidium

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Marusyk R G

Morgan A R

Wadell G

References (11)

11 references, click to expand

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Adenovirus endonuclease: association with the penton of adenovirus type 2.
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J Virol. 1969 Nov;4(5):671-80 PMID: 5360525
Separation and characterization of soluble adenovirus type 9 components.
J Virol. 1967 Dec;1(6):1101-8 PMID: 5630229
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J Mol Biol. 1967 Jul 14;27(1):87-106 PMID: 6033613
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Article Info

Journal

Journal of virology

Abbr.

J Virol

ISSN

0022-538X

DOI

10.1128/JVI.16.2.456-458.1975

Published

1975-08-00

Pages

456-8

Language

English

Region

United States

NLM ID

0113724

PMCID

PMC354685

Subset

External Links

PubMed source DOI: 10.1128/JVI.16.2.456-458.1975 PMC Full Text View journal details

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Association of endonuclease activity with serotypes belonging to the three subgroups of human adenoviruses.

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