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PMID: 11973317 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Contrasting evolutionary forces in the Arabidopsis thaliana floral developmental pathway.

Genetics ·Vol. 160 ·No. 4 ·2002-04-00 ·Pages 1641-50

Olsen KM, Womack A, Garrett AR, Suddith JI, Purugganan MD

Abstract

The floral developmental pathway in Arabidopsis thaliana is composed of several interacting regulatory genes, including the inflorescence architecture gene TERMINAL FLOWER1 (TFL1), the floral meristem identity genes LEAFY (LFY), APETALA1 (AP1), and CAULIFLOWER (CAL), and the floral organ identity genes APETALA3 (AP3) and PISTILLATA (PI). Molecular population genetic analyses of these different genes indicate that the coding regions of AP3 and PI, as well as AP1 and CAL, share similar levels and patterns of nucleotide diversity. In contrast, the coding regions of TFL1 and LFY display a significant reduction in nucleotide variation, suggesting that these sequences have been subjected to a recent adaptive sweep. Moreover, the promoter of TFL1, unlike its coding region, displays high levels of diversity organized into two distinct haplogroups that appear to be maintained by selection. These results suggest that patterns of molecular evolution differ among regulatory genes in this developmental pathway, with the earlier acting genes exhibiting evidence of adaptive evolution.

MeSH Terms
Arabidopsis/genetics Arabidopsis Proteins Base Sequence Biological Evolution Genetic Variation Homeodomain Proteins/genetics MADS Domain Proteins Molecular Sequence Data Plant Proteins/genetics Polymorphism, Genetic Promoter Regions, Genetic Transcription Factors
Chemicals
AP1 protein, Arabidopsis Arabidopsis Proteins Homeodomain Proteins LFY protein, Arabidopsis MADS Domain Proteins Plant Proteins TFL1 protein, Arabidopsis Transcription Factors
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Olsen Kenneth M
Department of Genetics, North Carolina State University, Raleigh, North Carolina 27695, USA.
Womack Andrew
Garrett Ashley R
Suddith Jane I
Purugganan Michael D
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Article Info
Journal
Genetics
Abbr.
Genetics
ISSN
0016-6731
DOI
10.1093/genetics/160.4.1641
Published
2002-04-00
Pages
1641-50
Language
English
Region
United States
NLM ID
0374636
PMCID
PMC1462059
Subset
IM
External Links
PubMed source DOI: 10.1093/genetics/160.4.1641 PMC Full Text View journal details
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