Ganglioside and rabbit erythrocyte membrane receptor for staphylococcal alpha-toxin.

Infection and immunity ·Vol. 13 ·No. 1 ·1976-01-00 ·Pages 289-91

Kato I, Naiki M

Abstract

The hemolytic activity of staphylococcal alpha-toxin is inhibited by an N-acetylglucosamine-containing ganglioside (GlcNAc-ganglioside) but not by any of the related glycolipids. The GlcNAc-ganglioside also is precipitated with the toxin by a gel-diffusion technique. It is postulated that GlcNAc-ganglioside may be the membrane receptor for the alpha-toxin.

MeSH Terms

Animals Cell Membrane/physiology Erythrocytes Gangliosides/pharmacology Hemolysis/drug effects Rabbits Receptors, Drug/drug effects Staphylococcus Toxins, Biological/metabolism

Chemicals

Gangliosides Receptors, Drug Toxins, Biological

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Kato I

Naiki M

References (15)

15 references, click to expand

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Article Info

Journal

Infection and immunity

Abbr.

Infect Immun

ISSN

0019-9567

DOI

10.1128/iai.13.1.289-291.1976

Published

1976-01-00

Pages

289-91

Language

English

Region

United States

NLM ID

0246127

PMCID

PMC420607

Subset

External Links

PubMed source DOI: 10.1128/iai.13.1.289-291.1976 PMC Full Text View journal details

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Ganglioside and rabbit erythrocyte membrane receptor for staphylococcal alpha-toxin.

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