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PMID: 1275576 Published · ppublish English Journal Article

Arthritis of mice induced by Mycoplasma arthritidis. Humoral antibody and lymphocyte responses of CBA mice.

Annals of the rheumatic diseases ·Vol. 35 ·No. 1 ·1976-02-00 ·Pages 14-22

Cole BC, Golightly-Rowland L, Ward JR

Abstract

Peak arthritis occurred 7 days after intravenous injection of CBA mice with Mycoplasma arthritidis and persisted in some animals for 84 days. A marked leucocytosis was apparent for the first 21 days. Complement-fixing antibodies reached a peak 14 days after injection of the organisms and persisted at high levels for 84 days. Metabolic-inhibiting and mycoplasmacidal antibodies were present but at much lower titres.

MeSH Terms
Animals Antibodies, Bacterial/analysis Antibody Formation Arthritis/etiology,immunology,microbiology Female Immunity, Cellular Lectins/pharmacology Lipopolysaccharides/pharmacology Lymphocyte Activation Mice Mice, Inbred CBA Mycoplasma/isolation & purification Mycoplasma Infections/immunology
Chemicals
Antibodies, Bacterial Lectins Lipopolysaccharides
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Cole B C
Golightly-Rowland L
Ward J R
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25 references, click to expand
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Article Info
Journal
Annals of the rheumatic diseases
Abbr.
Ann Rheum Dis
ISSN
0003-4967
DOI
10.1136/ard.35.1.14
Published
1976-02-00
Pages
14-22
Language
English
Region
England
NLM ID
0372355
PMCID
PMC1006500
Subset
IM
External Links
PubMed source DOI: 10.1136/ard.35.1.14 PMC Full Text View journal details
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