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PMID: 12867473 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Analysis of the interaction between the transcription factor sigmaG and the anti-sigma factor SpoIIAB of Bacillus subtilis.

Journal of bacteriology ·Vol. 185 ·No. 15 ·2003-08-00 ·Pages 4615-9

Evans L, Clarkson J, Yudkin MD, Errington J, Feucht A

Abstract

The activation of sigma(G), a transcription factor, in Bacillus subtilis is coupled to the completion of engulfment during sporulation. SpoIIAB, an anti-sigma factor involved in regulation of sigma(F), is also shown to form a complex with sigma(G) in vitro. SpoIIAA, the corresponding anti-anti-sigma factor, can disrupt the SpoIIAB:sigma(G) complex, releasing free sigma(G). The data suggest the existence of an as-yet-unknown mechanism to keep sigma(G) inactive prior to engulfment.

MeSH Terms
Bacillus subtilis/growth & development,metabolism,physiology Bacterial Proteins/metabolism Gene Expression Regulation, Bacterial Sigma Factor/metabolism Spores, Bacterial Transcription, Genetic
Chemicals
Bacterial Proteins Sigma Factor spore-specific proteins, Bacillus
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Evans Louise
Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, United Kingdom.
Clarkson Joanna
Yudkin Michael D
Errington Jeff
Feucht Andrea
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24 references, click to expand
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/JB.185.15.4615-4619.2003
Published
2003-08-00
Pages
4615-9
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC165760
Subset
IM
External Links
PubMed source DOI: 10.1128/JB.185.15.4615-4619.2003 PMC Full Text View journal details
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