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PMID: 14109864 Published · ppublish ger Journal Article

[THE SIGNIFICANCE OF THE FOLIC ACID METABOLISM FOR THE NORMAL AND PATHOLOGICAL MATURATION OF BLOOD CELLS].

DIE BEDEUTUNG DES FOLSAEURESTOFFWECHSELS FUER DIE NORMALE UND PATHOLOGISCHE REIFUNG VON BLUTZELLEN.

Klinische Wochenschrift ·Vol. 41 ·1963-11-15 ·Pages 1077-82

WILMANNS W, JAENICKE L

Abstract

暂无摘要

Keywords
BLOOD CELLS CITROVORUM FACTOR FOLIC ACID ISOMERASES LEUKEMIA MERCAPTOPURINE METABOLISM METHOTREXATE OXIDOREDUCTASES
MeSH Terms
Blood Cells Folic Acid Humans Isomerases Leucovorin Leukemia Mercaptopurine Metabolism Methotrexate Oxidoreductases
Chemicals
Folic Acid Mercaptopurine Oxidoreductases Isomerases Leucovorin Methotrexate
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
WILMANNS W
JAENICKE L
References (30)
30 references, click to expand
  1. A mechanism of resistance to 6-mercaptopurine: metabolism of hypoxanthine and 6-mercaptopurine by sensitive and resistant neoplasms.
    Cancer Res. 1960 Jun;20:643-53 PMID: 13804596
  2. Direct spectrophotometric evidence for the oxidation of tetrahydrofolate during the enzymatic synthesis of thymidylate.
    J Biol Chem. 1961 Mar;236:PC11-2 PMID: 13782537
  3. Specific action of adenine as a feedback inhibitor of purine biosynthesis.
    Science. 1959 Sep 11;130(3376):622-3 PMID: 13851425
  4. Enzymic formation of 6-mercaptopurine tibo tide.
    Biochim Biophys Acta. 1957 May;24(2):432-3 PMID: 13436452
  5. Metabolism of human leukocytes in vitro. II. The effect of several agents on the incorporation of radioactive formate and glycine.
    Cancer Res. 1959 May;19(4):377-87 PMID: 13652121
  6. A factor required for the growth of Leuconostoc citrovorum.
    J Biol Chem. 1948 Oct;176(1):165-73 PMID: 18886154
  7. Increased level of dihydrofolic reductase in leucocytes of patients treated with amethopterin.
    Nature. 1962 Jan 13;193:140-2 PMID: 13868435
  8. Relation of folic acid reductase to amethopterin resistance in cultured mammalian cells.
    J Biol Chem. 1961 Mar;236:952-8 PMID: 13710631
  9. Metabolism of resistant mutants of Streptococcus faecalis. III. The action of 6-mercaptopurine.
    Cancer Res. 1958 May;18(4):440-4 PMID: 13536995
  10. Biosynthesis of the purines. XXVI. The identification of the formyl donors of the transformylation reactions.
    J Biol Chem. 1959 Jul;234(7):1812-6 PMID: 13672969
  11. Purification and properties of folic acid reductase from chicken liver.
    J Biol Chem. 1960 Jun;235:1776-9 PMID: 13846873
  12. Evidence for the enzymic deacylation of N10-formyl tetrahydro-folic acid.
    Biochim Biophys Acta. 1957 Oct;26(1):208-10 PMID: 13479484
  13. The isolation of the Lactobacillus casei factor from liver.
    J Am Chem Soc. 1948 Jan;70(1):3-5 PMID: 18918784
  14. Metabolism of human leukocytes in vitro. III. Incorporation of formate-C14 into cellular components of leukemic human leukocytes.
    Cancer Res. 1959 Nov;19:1086-90 PMID: 13843909
  15. The role of the folate coenzymes in cellular division. A review.
    Cancer Res. 1962 Apr;22:267-81 PMID: 14480820
  16. Studies on the mechanism of action of 6-mercaptopurine in sensitive and resistant L1210 leukemia in vitro.
    Cancer Res. 1960 Feb;20:225-32 PMID: 13814343
  17. Effects of A-methopterin on nucleic acid synthesis in leukemia spleen breis.
    Cancer Res. 1955 Oct;15(9):603-8 PMID: 13261082
  18. Studies of the action of adenylosuccinase with 6-thio analogues of adenylosuccinic acid.
    J Biol Chem. 1962 Feb;237:529-35 PMID: 13904242
  19. [Indication for the treatment of acute leukemia by 6-mercaptopurine on biochemical basis].
    Dtsch Med Wochenschr. 1963 Apr 26;88:900-7 PMID: 14000986
  20. Some metabolic approaches to cancer chemotherapy.
    Cancer Res. 1961 Dec;21:1475-90 PMID: 14005959
  21. Increased dihydrofolate reductase activity as a possible basis of drug resistance in leukaemia.
    Nature. 1961 Jan 7;189:39-42 PMID: 13771292
  22. The enzymatic conversion of N5-formyl tetrahydrofolic acid (folinic acid) to N10-formyl tetrahydrofolic acid.
    J Biol Chem. 1960 Jan;235:195-201 PMID: 14404999
  23. [The tetrahydrofolic acid--dependent activation of single carbon units in normal and pathological white blood cells].
    Klin Wochenschr. 1961 Sep 1;39:884-8 PMID: 13785612
  24. [Research on monocarbon compounds. I. The tetrahydrofolate formylase from pigeon liver. Purification and mechanism].
    Biochem Z. 1961;334:108-32 PMID: 13789141
  25. Evidence for a single enzyme reducing folate and dihydrofolate.
    J Biol Chem. 1960 Oct;235:2984-8 PMID: 13787765
  26. The catabolism of C14-labeled beta-alanine in the intact rat.
    J Biol Chem. 1955 Jul;215(1):345-51 PMID: 14392168
  27. [Determination, properties and significance of dihydrofolic acid reductase in the white blood cells in leukemia].
    Klin Wochenschr. 1962 May 15;40:533-40 PMID: 14007297
  28. Enzymatic reduction of folic acid and dihydrofolic acid to tetrahydrofolic acid.
    J Biol Chem. 1957 Oct;228(2):1031-8 PMID: 13475378
  29. [FOLIC ACID METABOLISM AND ONE-CARBON UNITS].
    Klin Wochenschr. 1963 Nov 1;41:1030-8 PMID: 14098334
  30. Folic acid coenzymes.
    Fed Proc. 1960 Dec;19:963-70 PMID: 13738852
Article Info
Journal
Klinische Wochenschrift
Abbr.
Klin Wochenschr
ISSN
0023-2173
DOI
10.1007/BF01486507
Published
1963-11-15
Pages
1077-82
Language
ger
Region
Germany
NLM ID
2985205R
Subset
OM
External Links
PubMed source DOI: 10.1007/BF01486507
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