IMMUNOLOGIC TOLERANCE AFTER SPECIFIC IMMUNIZATION.

The Journal of experimental medicine ·Vol. 120 ·1964-09-01 ·Pages 435-47

DORNER MM, UHR JW

Abstract

Specific immunologic tolerance to bovine serum albumin (BSA) was induced in approximately one-half of the rabbits that had been primarily immunized and were prepared for a secondary antibody response to BSA. The state of tolerance lasted for several months in the majority of rabbits and was not easily terminated by immunization with human serum albumin followed by BSA.

Keywords

ANIMALS NEWBORN ANTIBODY FORMATION CATTLE EXPERIMENTAL LAB STUDY IMMUNE TOLERANCE IMMUNIZATION INJECTIONS INTRAPERITONEAL RABBITS SERUM ALBUMIN

MeSH Terms

Animals Animals, Newborn Antibody Formation Cattle Humans Immune Tolerance Immunization Injections Injections, Intraperitoneal Rabbits Research Serum Albumin Serum Albumin, Bovine Vaccination

Chemicals

Serum Albumin Serum Albumin, Bovine

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

DORNER M M

UHR J W

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29 references, click to expand

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Article Info

Journal

The Journal of experimental medicine

Abbr.

J Exp Med

ISSN

0022-1007

DOI

10.1084/jem.120.3.435

Published

1964-09-01

Pages

435-47

Language

English

Region

United States

NLM ID

2985109R

PMCID

PMC2137760

Subset

External Links

PubMed source DOI: 10.1084/jem.120.3.435 PMC Full Text View journal details

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