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PMID: 14681377 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Recent improvements to the PROSITE database.

Nucleic acids research ·Vol. 32 ·No. Database issue ·2004-01-01 ·Pages D134-7

Hulo N, Sigrist CJ, Le Saux V, Langendijk-Genevaux PS, Bordoli L, Gattiker A, De Castro E, Bucher P, Bairoch A

Abstract

The PROSITE database consists of a large collection of biologically meaningful signatures that are described as patterns or profiles. Each signature is linked to documentation that provides useful biological information on the protein family, domain or functional site identified by the signature. The PROSITE web page has been redesigned and several tools have been implemented to help the user discover new conserved regions in their own proteins and to visualize domain arrangements. We also introduced the facility to search PDB with a PROSITE entry or a user's pattern and visualize matched positions on 3D structures. The latest version of PROSITE (release 18.17 of November 30, 2003) contains 1676 entries. The database is accessible at http://www.expasy.org/prosite/.

MeSH Terms
Amino Acid Motifs Animals Computational Biology Conserved Sequence Databases, Protein Humans Internet Models, Molecular Protein Structure, Tertiary Proteins/chemistry,metabolism Quality Control Sequence Alignment Structure-Activity Relationship
Chemicals
Proteins
Authors & Affiliations
9 authors, click to expand affiliations / ORCID
Hulo Nicolas
Swiss Institute of Bioinformatics (SIB), CMU, University of Geneva, 1 rue Michel Servet, 1211 Geneva 4, Switzerland. [email protected]
Sigrist Christian J A
Le Saux Virginie
Langendijk-Genevaux Petra S
Bordoli Lorenza
Gattiker Alexandre
De Castro Edouard
Bucher Philipp
Bairoch Amos
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Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
1362-4962
DOI
10.1093/nar/gkh044
Email
[email protected]
Published
2004-01-01
Pages
D134-7
Language
English
Region
England
NLM ID
0411011
PMCID
PMC308778
Subset
IM
External Links
PubMed source DOI: 10.1093/nar/gkh044 PMC Full Text View journal details
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