-
Cloning of a novel inosine-guanosine transporter gene from Leishmania donovani by functional rescue of a transport-deficient mutant.
J Biol Chem. 2000 Jul 7;275(27):20935-41
PMID: 10783393
-
The specificity of purine base and nucleoside uptake in promastigotes of Leishmania braziliensis panamensis.
Parasitology. 1982 Oct;85 (Pt 2):271-82
PMID: 7145470
-
Probing structure of neurotransmitter transporters by substituted-cysteine accessibility method.
Methods Enzymol. 1998;296:331-46
PMID: 9779459
-
Chimeric constructs between human and rat equilibrative nucleoside transporters (hENT1 and rENT1) reveal hENT1 structural domains interacting with coronary vasoactive drugs.
J Biol Chem. 1998 Aug 21;273(34):21519-25
PMID: 9705281
-
Point mutations in a nucleoside transporter gene from Leishmania donovani confer drug resistance and alter substrate selectivity.
Proc Natl Acad Sci U S A. 2001 May 22;98(11):6092-7
PMID: 11353834
-
Mechanisms of arsenical and diamidine uptake and resistance in Trypanosoma brucei.
Eukaryot Cell. 2003 Oct;2(5):1003-8
PMID: 14555482
-
Crithidia luciliae: regulation of purine nucleoside transport by extracellular purine concentrations.
Exp Parasitol. 1996 Aug;83(3):314-21
PMID: 8823248
-
Two high affinity nucleoside transporters in Leishmania donovani.
Mol Biochem Parasitol. 1987 Jan 2;22(1):29-37
PMID: 3807949
-
Genetic analysis of nucleoside transport in Leishmania donovani.
Mol Cell Biol. 1984 Jun;4(6):1013-9
PMID: 6234454
-
Characterisation of the growth and differentiation in vivo and in vitro-of bloodstream-form Trypanosoma brucei strain TREU 927.
Mol Biochem Parasitol. 2001 Feb;112(2):163-71
PMID: 11223123
-
Sinefungin shares AdoMet-uptake system to enter Leishmania donovani promastigotes.
Biochem J. 1995 Jan 1;305 ( Pt 1):133-7
PMID: 7826320
-
The adenosine transporter of Toxoplasma gondii. Identification by insertional mutagenesis, cloning, and recombinant expression.
J Biol Chem. 1999 Dec 3;274(49):35255-61
PMID: 10575012
-
Identification of Cys140 in helix 4 as an exofacial cysteine residue within the substrate-translocation channel of rat equilibrative nitrobenzylthioinosine (NBMPR)-insensitive nucleoside transporter rENT2.
Biochem J. 2001 Jan 15;353(Pt 2):387-93
PMID: 11139404
-
Purine nucleobase transport in bloodstream forms of Trypanosoma brucei is mediated by two novel transporters.
Mol Biochem Parasitol. 1997 Nov;89(2):245-58
PMID: 9364969
-
Topology of a human equilibrative, nitrobenzylthioinosine (NBMPR)-sensitive nucleoside transporter (hENT1) implicated in the cellular uptake of adenosine and anti-cancer drugs.
J Biol Chem. 2001 Nov 30;276(48):45270-5
PMID: 11584005
-
Nucleoside transporters: molecular biology and implications for therapeutic development.
Mol Med Today. 1999 May;5(5):216-24
PMID: 10322314
-
Neurotransmitter transport: models in flux.
Proc Natl Acad Sci U S A. 1998 Oct 27;95(22):12737-8
PMID: 9788979
-
Arsenical-resistant trypanosomes lack an unusual adenosine transporter.
Nature. 1993 Jan 14;361(6408):173-6
PMID: 8421523
-
Hypoxanthine uptake through a purine-selective nucleobase transporter in Trypanosoma brucei brucei procyclic cells is driven by protonmotive force.
Eur J Biochem. 1997 Aug 1;247(3):1102-10
PMID: 9288936
-
Isolation and functional characterization of the PfNT1 nucleoside transporter gene from Plasmodium falciparum.
J Biol Chem. 2000 Apr 7;275(14):10683-91
PMID: 10744765
-
Purine analogs as chemotherapeutic agents in leishmaniasis and American trypanosomiasis.
J Lab Clin Med. 1991 Aug;118(2):111-9
PMID: 1906917
-
Differential regulation of nucleoside and nucleobase transporters in Crithidia fasciculata and Trypanosoma brucei brucei.
Mol Biochem Parasitol. 2000 Feb 25;106(1):93-107
PMID: 10743614
-
Substrate depletion upregulates uptake of myo-inositol, glucose and adenosine in Leishmania.
Mol Biochem Parasitol. 1999 Oct 25;104(1):121-30
PMID: 10589986
-
A nucleoside transporter from Trypanosoma brucei involved in drug resistance.
Science. 1999 Jul 9;285(5425):242-4
PMID: 10398598
-
Molecular cloning and functional characterization of nitrobenzylthioinosine (NBMPR)-sensitive (es) and NBMPR-insensitive (ei) equilibrative nucleoside transporter proteins (rENT1 and rENT2) from rat tissues.
J Biol Chem. 1997 Nov 7;272(45):28423-30
PMID: 9353301
-
Genetic variants of the TbAT1 adenosine transporter from African trypanosomes in relapse infections following melarsoprol therapy.
Mol Biochem Parasitol. 2001 Sep 28;117(1):73-81
PMID: 11551633
-
Mutation of residue 33 of human equilibrative nucleoside transporters 1 and 2 alters sensitivity to inhibition of transport by dilazep and dipyridamole.
J Biol Chem. 2002 Jan 4;277(1):395-401
PMID: 11689555
-
Characterization of a nucleoside/proton symporter in procyclic Trypanosoma brucei brucei.
J Biol Chem. 1998 Apr 17;273(16):9486-94
PMID: 9545276
-
The kamikaze approach to membrane transport.
Nat Rev Mol Cell Biol. 2001 Aug;2(8):610-20
PMID: 11483994
-
Nucleoside uptake in Trypanosoma cruzi: analysis of a mutant resistant to tubercidin.
Mol Biochem Parasitol. 1988 Nov;31(2):133-40
PMID: 3054542
-
Stage-specific development of a novel adenosine transporter in Leishmania donovani amastigotes.
Mol Biochem Parasitol. 2000 Apr 30;108(1):93-9
PMID: 10802321
-
Nucleobase transporters (review).
Mol Membr Biol. 2000 Apr-Jun;17(2):75-94
PMID: 10989458
-
The ENT family of eukaryote nucleoside and nucleobase transporters: recent advances in the investigation of structure/function relationships and the identification of novel isoforms.
Mol Membr Biol. 2001 Jan-Mar;18(1):53-63
PMID: 11396612
-
Enhanced acquisition of purine nucleosides and nucleobases by purine-starved Crithidia luciliae.
Mol Biochem Parasitol. 1996 Feb-Mar;76(1-2):279-87
PMID: 8920013
-
A unique transporter of S-adenosylmethionine in African trypanosomes.
FASEB J. 1997 Mar;11(4):256-60
PMID: 9068614
-
Cloning of Leishmania nucleoside transporter genes by rescue of a transport-deficient mutant.
Proc Natl Acad Sci U S A. 1998 Aug 18;95(17):9873-8
PMID: 9707568
-
Cloning, heterologous expression, and in situ characterization of the first high affinity nucleobase transporter from a protozoan.
J Biol Chem. 2003 Jun 27;278(26):23502-7
PMID: 12707261
-
Cloning and functional expression of a gene encoding a P1 type nucleoside transporter from Trypanosoma brucei.
J Biol Chem. 1999 Oct 15;274(42):30244-9
PMID: 10514517
-
A Leishmania major nucleobase transporter responsible for allopurinol uptake is a functional homolog of the Trypanosoma brucei H2 transporter.
Mol Pharmacol. 2003 Apr;63(4):814-20
PMID: 12644582
-
Six related nucleoside/nucleobase transporters from Trypanosoma brucei exhibit distinct biochemical functions.
J Biol Chem. 2002 Jun 14;277(24):21499-504
PMID: 11937511
-
Crithidia luciliae: functional expression of nucleoside and nucleobase transporters in Xenopus laevis oocytes.
Exp Parasitol. 1998 Oct;90(2):181-8
PMID: 9769248
-
Equilibrative nucleoside transporter family members from Leishmania donovani are electrogenic proton symporters.
J Biol Chem. 2003 Sep 12;278(37):35127-34
PMID: 12835315
-
Identification of a nucleoside/nucleobase transporter from Plasmodium falciparum, a novel target for anti-malarial chemotherapy.
Biochem J. 2000 Jul 1;349(Pt 1):67-75
PMID: 10861212
-
Uptake of diamidine drugs by the P2 nucleoside transporter in melarsen-sensitive and -resistant Trypanosoma brucei brucei.
J Biol Chem. 1995 Nov 24;270(47):28153-7
PMID: 7499305
-
Localization of the Plasmodium falciparum PfNT1 nucleoside transporter to the parasite plasma membrane.
J Biol Chem. 2001 Nov 2;276(44):41095-9
PMID: 11682491
-
A drug resistance determinant in Trypanosoma brucei.
Trends Microbiol. 1999 Dec;7(12):469-71
PMID: 10603477
-
Molecular and functional characterization of the first nucleobase transporter gene from African trypanosomes.
Mol Biochem Parasitol. 2003 Aug 31;130(2):101-10
PMID: 12946846
-
Pyrazolopyrimidine metabolism in parasitic protozoa.
Pharm Res. 1984 Sep;1(5):194-203
PMID: 24277328
-
Functional expression and characterization of a purine nucleobase transporter gene from Leishmania major.
Mol Membr Biol. 2004 Jan-Feb;21(1):11-8
PMID: 14668134
-
Functional analysis of an inosine-guanosine transporter from Leishmania donovani. The role of conserved residues, aspartate 389 and arginine 393.
J Biol Chem. 2003 Aug 29;278(35):33327-33
PMID: 12807872
-
Reduced purine accumulation is encoded on an amplified DNA in Leishmania mexicana amazonensis resistant to toxic nucleosides.
Mol Biochem Parasitol. 1993 Aug;60(2):171-85
PMID: 8232410
-
A highly selective, high-affinity transporter for uracil in Trypanosoma brucei brucei: evidence for proton-dependent transport.
Biochem Cell Biol. 1998;76(5):853-8
PMID: 10353720
-
Molecular evolution of the equilibrative nucleoside transporter family: identification of novel family members in prokaryotes and eukaryotes.
Mol Biol Evol. 2002 Dec;19(12):2199-210
PMID: 12446811