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PMID: 15996988 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S.

Tempos of gene locus deletions and duplications and their relationship to recombination rate during diploid and polyploid evolution in the Aegilops-Triticum alliance.

Genetics ·Vol. 171 ·No. 1 ·2005-09-00 ·Pages 323-32

Dvorak J, Akhunov ED

Abstract

The origin of tetraploid wheat and the divergence of diploid ancestors of wheat A and D genomes were estimated to have occurred 0.36 and 2.7 million years ago, respectively. These estimates and the evolutionary history of 3159 gene loci were used to estimate the rates with which gene loci have been deleted and duplicated during the evolution of wheat diploid ancestors and during the evolution of polyploid wheat. During diploid evolution, the deletion rate was 2.1 x 10(-3) locus(-1) MY(-1) for single-copy loci and 1.0 x 10(-2) locus(-1) MY(-1) for loci in paralogous sets. Loci were duplicated with a rate of 2.9 x 10(-3) locus(-1) MY(-1) during diploid evolution. During polyploid evolution, locus deletion and locus duplication rates were 1.8 x 10(-2) and 1.8 x 10(-3) locus(-1) MY(-1), respectively. Locus deletion and duplication rates correlated positively with the distance of the locus from the centromere and the recombination rate during diploid evolution. The functions of deleted and duplicated loci were inferred to gain insight into the surprisingly high rate of deletions of loci present apparently only once in a genome. The significance of these findings for genome evolution at the diploid and polyploid level is discussed.

MeSH Terms
Centromere/genetics Chromosome Mapping Chromosomes, Plant/genetics Diploidy Evolution, Molecular Gene Deletion Gene Duplication Genetic Variation Genome, Plant Linear Models Molecular Sequence Data Phylogeny Plant Proteins/genetics Poaceae/genetics Polyploidy Recombination, Genetic Time Factors Triticum/genetics
Chemicals
Plant Proteins
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Dvorak Jan
Department of Plant Sciences, University of California, Davis, California 95616, USA. [email protected]
Akhunov Eduard D
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Article Info
Journal
Genetics
Abbr.
Genetics
ISSN
0016-6731
DOI
10.1534/genetics.105.041632
Email
[email protected]
Published
2005-09-00
Epub
2005-00-04
Pages
323-32
Language
English
Region
United States
NLM ID
0374636
PMCID
PMC1456522
Subset
IM
Databases
GENBANK
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External Links
PubMed source DOI: 10.1534/genetics.105.041632 PMC Full Text View journal details
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