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PMID: 16381852 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

The PROSITE database.

Nucleic acids research ·Vol. 34 ·No. Database issue ·2006-01-01 ·Pages D227-30

Hulo N, Bairoch A, Bulliard V, Cerutti L, De Castro E, Langendijk-Genevaux PS, Pagni M, Sigrist CJ

Abstract

The PROSITE database consists of a large collection of biologically meaningful signatures that are described as patterns or profiles. Each signature is linked to a documentation that provides useful biological information on the protein family, domain or functional site identified by the signature. The PROSITE database is now complemented by a series of rules that can give more precise information about specific residues. During the last 2 years, the documentation and the ScanProsite web pages were redesigned to add more functionalities. The latest version of PROSITE (release 19.11 of September 27, 2005) contains 1329 patterns and 552 profile entries. Over the past 2 years more than 200 domains have been added, and now 52% of UniProtKB/Swiss-Prot entries (release 48.1 of September 27, 2005) have a cross-reference to a PROSITE entry. The database is accessible at http://www.expasy.org/prosite/.

MeSH Terms

Amino Acids/chemistry Databases, Protein Internet Protein Structure, Tertiary Proteins/chemistry,classification Software User-Computer Interface

Chemicals

Amino Acids Proteins

Authors & Affiliations

8 authors, click to expand affiliations / ORCID

Hulo Nicolas

Swiss Institute of Bioinformatics (SIB), Centre Medical Universitaire, 1 rue Michel Servet, 1211 Geneva 4, Switzerland. [email protected]

Bairoch Amos

Bulliard Virginie

Cerutti Lorenzo

De Castro Edouard

Langendijk-Genevaux Petra S

Pagni Marco

Sigrist Christian J A

References (8)

8 references, click to expand

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Article Info

Journal

Nucleic acids research

Abbr.

Nucleic Acids Res

ISSN

1362-4962

DOI

10.1093/nar/gkj063

[email protected]

Published

2006-01-01

Pages

D227-30

Language

English

Region

England

NLM ID

0411011

PMCID

PMC1347426

Subset

External Links

PubMed source DOI: 10.1093/nar/gkj063 PMC Full Text View journal details

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