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PMID: 16439323 Published · ppublish English Letter

New insights into the antiviral effects of chloroquine.

The Lancet. Infectious diseases ·Vol. 6 ·No. 2 ·2006-02-00 ·Pages 67-9

Savarino A, Di Trani L, Donatelli I, Cauda R, Cassone A

Abstract

暂无摘要

MeSH Terms
Anti-HIV Agents/therapeutic use Antimalarials/therapeutic use Antiviral Agents/therapeutic use Chloroquine/therapeutic use Dose-Response Relationship, Drug Drug Therapy, Combination Enzyme Inhibitors/therapeutic use HIV Infections/drug therapy HIV-1 Humans Hydroxychloroquine/therapeutic use Severe Acute Respiratory Syndrome/drug therapy Treatment Outcome Viral Load Virus Replication/drug effects
Chemicals
Anti-HIV Agents Antimalarials Antiviral Agents Enzyme Inhibitors Hydroxychloroquine Chloroquine
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Savarino Andrea
Di Trani Livia
Donatelli Isabella
Cauda Roberto
Cassone Antonio
References (13)
13 references, click to expand
  1. Low cost anti-retroviral options: chloroquine based ARV regimen combined with hydroxyurea and lamivudine: a new economical triple therapy.
    J Assoc Physicians India. 2004 Jul;52:597-8 PMID: 15645995
  2. Development and validation of a genetic algorithm for flexible docking.
    J Mol Biol. 1997 Apr 4;267(3):727-48 PMID: 9126849
  3. Antihistaminics, local anesthetics, and other amines as antiviral agents.
    Proc Natl Acad Sci U S A. 1981 Jun;78(6):3605-9 PMID: 6115382
  4. Hydroxychloroquine, hydroxyurea and didanosine as initial therapy for HIV-infected patients with low viral load: safety, efficacy and resistance profile after 144 weeks.
    HIV Med. 2005 Jan;6(1):13-20 PMID: 15670247
  5. In vitro inhibition of severe acute respiratory syndrome coronavirus by chloroquine.
    Biochem Biophys Res Commun. 2004 Oct 8;323(1):264-8 PMID: 15351731
  6. Mechanism of uncoating of influenza B virus in MDCK cells: action of chloroquine.
    J Gen Virol. 1983 May;64(Pt 5):1149-56 PMID: 6842189
  7. Characterization of H5N2 influenza viruses from Italian poultry.
    J Gen Virol. 2001 Mar;82(Pt 3):623-630 PMID: 11172104
  8. Chloroquine is a potent inhibitor of SARS coronavirus infection and spread.
    Virol J. 2005 Aug 22;2:69 PMID: 16115318
  9. Anti-HIV effects of chloroquine: inhibition of viral particle glycosylation and synergism with protease inhibitors.
    J Acquir Immune Defic Syndr. 2004 Mar 1;35(3):223-32 PMID: 15076236
  10. Kinetic mechanism of quinone oxidoreductase 2 and its inhibition by the antimalarial quinolines.
    Biochemistry. 2004 Apr 20;43(15):4538-47 PMID: 15078100
  11. Avian influenza and sialic acid receptors: more than meets the eye?
    Lancet Infect Dis. 2005 Mar;5(3):184-8 PMID: 15766653
  12. Optimal suppression of HIV replication by low-dose hydroxyurea through the combination of antiviral and cytostatic ('virostatic') mechanisms.
    AIDS. 2005 Jul 22;19(11):1173-81 PMID: 15990570
  13. Effects of chloroquine on viral infections: an old drug against today's diseases?
    Lancet Infect Dis. 2003 Nov;3(11):722-7 PMID: 14592603
Article Info
Journal
The Lancet. Infectious diseases
Abbr.
Lancet Infect Dis
ISSN
1473-3099
Published
2006-02-00
Pages
67-9
Language
English
Region
United States
NLM ID
101130150
PMCID
PMC7129107
Subset
IM
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