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PMID: 166981 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Mechanism of the isomerization of isopentenyl pyrophosphate in Rhodotorual rubra-1.

Journal of bacteriology ·Vol. 123 ·No. 1 ·1975-07-00 ·Pages 385-6

Hayman EP, Chichester CO, Simpson KL

Abstract

Stereospecifically labeled mevalonic acid was incorporated into the carotenoids of Rhodotorula. The randomized results are discussed in relation to mechanisms proposed for the conversion of isopentenyl pyrophosphate to dimethylallyl pyrophosphate and the prenol transferase enzyme system to Rhondotorula rubra.

MeSH Terms
Alkenes/metabolism Carotenoids/biosynthesis Hemiterpenes Isomerases/metabolism Isomerism Mevalonic Acid/metabolism Mitosporic Fungi/metabolism Organophosphorus Compounds/metabolism Phosphoric Acids/metabolism Rhodotorula/metabolism Transferases/metabolism
Chemicals
Alkenes Hemiterpenes Organophosphorus Compounds Phosphoric Acids isopentenyl pyrophosphate Carotenoids Transferases Isomerases Mevalonic Acid
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Hayman E P
Chichester C O
Simpson K L
References (5)
5 references, click to expand
  1. Sterol biosynthesis.
    Biochem Soc Symp. 1970;29:45-77 PMID: 4944437
  2. Aspects of the stereochemistry of torularhodin biosynthesis.
    Biochem J. 1970 May;117(5):921-7 PMID: 5465554
  3. THE PARTIAL PURIFICATION, PROPERTIES, AND MECHANISM OF ACTION OF PIG LIVER ISOPENTENYL PYROPHOSPHATE ISOMERASE.
    J Biol Chem. 1965 May;240:1946-56 PMID: 14299613
  4. Substrate stereochemistry in squalene biosynthesis: The first Ciba medal lecture.
    Biochem J. 1966 Dec;101(3):553.b4-568 PMID: 16742426
  5. Biosynthesis of carotenoids and plant triterpenes.
    Biochem J. 1971 Jul;123(3):293-329 PMID: 4331177
Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.123.1.385-386.1975
Published
1975-07-00
Pages
385-6
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC235733
Subset
IM
External Links
PubMed source DOI: 10.1128/jb.123.1.385-386.1975 PMC Full Text View journal details
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