Home LiteratureArticle Details
PMID: 17030821 Published · ppublish English Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

A beta2-frequency (20-30 Hz) oscillation in nonsynaptic networks of somatosensory cortex.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 103 ·No. 42 ·2006-10-17 ·Pages 15646-50

Roopun AK, Middleton SJ, Cunningham MO, LeBeau FE, Bibbig A, Whittington MA, Traub RD

Abstract

Beta2 frequency (20-30 Hz) oscillations appear over somatosensory and motor cortices in vivo during motor preparation and can be coherent with muscle electrical activity. We describe a beta2 frequency oscillation occurring in vitro in networks of layer V pyramidal cells, the cells of origin of the corticospinal tract. This beta2 oscillation depends on gap junctional coupling, but it survives a cut through layer 4 and, hence, does not depend on apical dendritic electrogenesis. It also survives a blockade of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors or a blockade of GABA(A) receptors that is sufficient to suppress gamma (30-70 Hz) oscillations in superficial cortical layers. The oscillation period is determined by the M type of K+ current.

MeSH Terms
Action Potentials/physiology Animals Beta Rhythm Excitatory Amino Acid Agonists/metabolism Gap Junctions/metabolism Kainic Acid/metabolism Male Nerve Net/physiology Neurons/cytology,metabolism Rats Rats, Wistar Receptors, GABA-A/metabolism Somatosensory Cortex/anatomy & histology,physiology alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid/metabolism
Chemicals
Excitatory Amino Acid Agonists Receptors, GABA-A alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Kainic Acid
Authors & Affiliations
7 authors, click to expand affiliations / ORCID
Roopun Anita K
Medical School, University of Newcastle, Newcastle NE2 4HH, United Kingdom.
Middleton Steven J
Cunningham Mark O
LeBeau Fiona E N
Bibbig Andrea
Whittington Miles A
Traub Roger D
References (28)
28 references, click to expand
  1. Oscillations in the premotor cortex: single-unit activity from awake, behaving monkeys.
    Exp Brain Res. 2000 Jan;130(2):195-215 PMID: 10672473
  2. Region-specific reduction in entorhinal gamma oscillations and parvalbumin-immunoreactive neurons in animal models of psychiatric illness.
    J Neurosci. 2006 Mar 8;26(10):2767-76 PMID: 16525056
  3. Axo-axonal coupling. a novel mechanism for ultrafast neuronal communication.
    Neuron. 2001 Sep 13;31(5):831-40 PMID: 11567620
  4. M channel KCNQ2 subunits are localized to key sites for control of neuronal network oscillations and synchronization in mouse brain.
    J Neurosci. 2001 Dec 15;21(24):9529-40 PMID: 11739564
  5. Ion channel properties underlying axonal action potential initiation in pyramidal neurons.
    Nat Neurosci. 2002 Jun;5(6):533-8 PMID: 11992119
  6. Neuronal metabolism governs cortical network response state.
    Proc Natl Acad Sci U S A. 2006 Apr 4;103(14):5597-601 PMID: 16565217
  7. Coherent oscillations in neuronal activity of the supplementary motor area during a visuomotor task.
    J Neurosci. 2003 Jul 30;23(17):6798-809 PMID: 12890774
  8. Synchronous, focally modulated beta-band oscillations characterize local field potential activity in the striatum of awake behaving monkeys.
    J Neurosci. 2003 Dec 17;23(37):11741-52 PMID: 14684876
  9. A role for fast rhythmic bursting neurons in cortical gamma oscillations in vitro.
    Proc Natl Acad Sci U S A. 2004 May 4;101(18):7152-7 PMID: 15103017
  10. Exact cortical extent of the origin of the corticospinal tract (CST) and the quantitative contribution to the CST in different cytoarchitectonic areas. A study with horseradish peroxidase in the monkey.
    J Hirnforsch. 1982;23(3):257-69 PMID: 7130676
  11. Effects of 4-aminopyridine on rapidly and slowly conducting axons of rat corpus callosum.
    Exp Neurol. 1983 Mar;79(3):808-20 PMID: 6825765
  12. Incidence of neuronal dye-coupling in neocortical slices depends on the plane of section.
    Neuroscience. 1985 Jul;15(3):659-66 PMID: 3906427
  13. Stimulus-specific neuronal oscillations in orientation columns of cat visual cortex.
    Proc Natl Acad Sci U S A. 1989 Mar;86(5):1698-702 PMID: 2922407
  14. Cellular mechanisms of 4-aminopyridine-induced synchronized after-discharges in the rat hippocampal slice.
    J Physiol. 1995 Nov 15;489 ( Pt 1):127-40 PMID: 8583397
  15. Synchronization of fast (30-40 Hz) spontaneous oscillations in intrathalamic and thalamocortical networks.
    J Neurosci. 1996 Apr 15;16(8):2788-808 PMID: 8786454
  16. Field potential oscillatory bursts in parietal cortex before and during reach.
    Brain Res. 1995 Dec 18;704(2):167-74 PMID: 8788911
  17. Coherent oscillations in monkey motor cortex and hand muscle EMG show task-dependent modulation.
    J Physiol. 1997 May 15;501 ( Pt 1):225-41 PMID: 9175005
  18. Electrical coupling underlies high-frequency oscillations in the hippocampus in vitro.
    Nature. 1998 Jul 9;394(6689):189-92 PMID: 9671303
  19. KCNQ2 and KCNQ3 potassium channel subunits: molecular correlates of the M-channel.
    Science. 1998 Dec 4;282(5395):1890-3 PMID: 9836639
  20. Perception's shadow: long-distance synchronization of human brain activity.
    Nature. 1999 Feb 4;397(6718):430-3 PMID: 9989408
  21. Gamma-band oscillations in the "barrel cortex" precede rat's exploratory whisking.
    Neuroscience. 1999;88(3):667-71 PMID: 10363807
  22. High-frequency population oscillations are predicted to occur in hippocampal pyramidal neuronal networks interconnected by axoaxonal gap junctions.
    Neuroscience. 1999;92(2):407-26 PMID: 10408594
  23. The role of synchrony and oscillations in the motor output.
    Exp Brain Res. 1999 Sep;128(1-2):109-17 PMID: 10473748
  24. Single-column thalamocortical network model exhibiting gamma oscillations, sleep spindles, and epileptogenic bursts.
    J Neurophysiol. 2005 Apr;93(4):2194-232 PMID: 15525801
  25. Temporal activation pattern of parietal and premotor areas related to praxis movements.
    Clin Neurophysiol. 2005 May;116(5):1201-12 PMID: 15826863
  26. Rapid developmental switch in the mechanisms driving early cortical columnar networks.
    Nature. 2006 Jan 5;439(7072):79-83 PMID: 16327778
  27. Excitatory effect of GABAergic axo-axonic cells in cortical microcircuits.
    Science. 2006 Jan 13;311(5758):233-5 PMID: 16410524
  28. Corticothalamic resonance, states of vigilance and mentation.
    Neuroscience. 2000;101(2):243-76 PMID: 11074149
Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
DOI
10.1073/pnas.0607443103
Published
2006-10-17
Epub
2006-00-09
Pages
15646-50
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC1592532
Subset
IM
Grants
Wellcome Trust · United Kingdom
External Links
PubMed source DOI: 10.1073/pnas.0607443103 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2