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PMID: 17209126 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S.

The indeterminate gametophyte1 gene of maize encodes a LOB domain protein required for embryo Sac and leaf development.

The Plant cell ·Vol. 19 ·No. 1 ·2007-01-00 ·Pages 46-62

Evans MM

Abstract

Angiosperm embryo sac development begins with a phase of free nuclear division followed by cellularization and differentiation of cell types. The indeterminate gametophyte1 (ig1) gene of maize (Zea mays) restricts the proliferative phase of female gametophyte development. ig1 mutant female gametophytes have a prolonged phase of free nuclear divisions leading to a variety of embryo sac abnormalities, including extra egg cells, extra polar nuclei, and extra synergids. Positional cloning of ig1 was performed based on the genome sequence of the orthologous region in rice. ig1 encodes a LATERAL ORGAN BOUNDARIES domain protein with high similarity to ASYMMETRIC LEAVES2 of Arabidopsis thaliana. A second mutant allele of ig1 was identified in a noncomplementation screen using active Mutator transposable element lines. Homozygous ig1 mutants have abnormal leaf morphology as well as abnormal embryo sac development. Affected leaves have disrupted abaxial-adaxial polarity and fail to repress the expression of meristem-specific knotted-like homeobox (knox) genes in leaf primordia, causing a proliferative, stem cell identity to persist in these cells. Despite the superficial similarity of ig1-O leaves and embryo sacs, ectopic knox gene expression cannot be detected in ig1-O embryo sacs.

MeSH Terms
Amino Acid Sequence Arabidopsis Proteins/chemistry Cell Proliferation Chromosome Mapping Cloning, Molecular Homeodomain Proteins/genetics,metabolism Molecular Sequence Data Multigene Family Mutation Phenotype Phylogeny Plant Leaves/cytology,growth & development,metabolism Plant Proteins/chemistry,genetics,physiology Protein Structure, Tertiary RNA, Messenger/metabolism Seeds/cytology,growth & development,metabolism Sequence Alignment Stem Cells/cytology,metabolism Transcription Factors/chemistry Zea mays/embryology,genetics,growth & development
Chemicals
AS2 protein, Arabidopsis Arabidopsis Proteins Homeodomain Proteins Plant Proteins RNA, Messenger Transcription Factors
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Evans Matthew M S
Department of Plant Biology, Carnegie Institution of Washington, Stanford, California 94305, USA. [email protected]
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Article Info
Journal
The Plant cell
Abbr.
Plant Cell
ISSN
1040-4651
DOI
10.1105/tpc.106.047506
Email
[email protected]
Published
2007-01-00
Epub
2007-00-05
Pages
46-62
Language
English
Region
England
NLM ID
9208688
PMCID
PMC1820972
Subset
IM
Databases
GENBANK
EF081454, EF081455
External Links
PubMed source DOI: 10.1105/tpc.106.047506 PMC Full Text View journal details
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