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PMID: 1729255 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Fumarate or a fumarate metabolite restores switching ability to rotating flagella of bacterial envelopes.

Journal of bacteriology ·Vol. 174 ·No. 2 ·1992-01-00 ·Pages 643-5

Barak R, Eisenbach M

Abstract

Flagella of cytoplasm-free envelopes of Escherichia coli or Salmonella typhimurium can rotate in either the counterclockwise or clockwise direction, but they never switch from one direction of rotation to another. Exogenous fumarate, in the intracellular presence of the chemotaxis protein CheY, restored switching ability to envelopes, with a concomitant increase in clockwise rotation. An increase in clockwise rotation was also observed after fumarate was added to partially lysed cells of E. coli, but the proportion of switching cells remained unchanged.

MeSH Terms
Cell Membrane/drug effects Cell Wall/drug effects Chemotaxis/drug effects Escherichia coli/drug effects Flagella/drug effects Fumarates/metabolism,pharmacology
Chemicals
Fumarates fumaric acid
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Barak R
Department of Membrane Research and Biophysics, Weizmann Institute of Science, Rehovot, Israel.
Eisenbach M
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27 references, click to expand
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.174.2.643-645.1992
Published
1992-01-00
Pages
643-5
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC205763
Subset
IM
Grants
NIAID NIH HHS · AI24675 · United States
External Links
PubMed source DOI: 10.1128/jb.174.2.643-645.1992 PMC Full Text View journal details
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