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PMID: 17513164 Published · ppublish English Journal Article Research Support, N.I.H., Extramural Review

A long and winding road: the Plasmodium sporozoite's journey in the mammalian host.

Parasitology international ·Vol. 56 ·No. 3 ·2007-09-00 ·Pages 171-8

Sinnis P, Coppi A

Abstract

The Plasmodium sporozoite, the infectious stage of the malaria parasite, makes a remarkable journey in its mammalian host. Here we review our current knowledge of the molecular and cellular basis of this journey, which begins in the skin and ends in the hepatocyte.

MeSH Terms
Animals Hepatocytes/parasitology Host-Parasite Interactions Humans Plasmodium/classification,genetics,metabolism,physiology Protozoan Proteins/genetics,metabolism Skin/parasitology Sporozoites/metabolism,physiology
Chemicals
Protozoan Proteins
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Sinnis Photini
Department of Medical Parasitology, New York University School of Medicine, 341 East 25th Street, New York, NY 10010, United States. [email protected]
Coppi Alida
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Article Info
Journal
Parasitology international
Abbr.
Parasitol Int
ISSN
1383-5769
DOI
10.1016/j.parint.2007.04.002
Email
[email protected]
Published
2007-09-00
Epub
2007-00-24
Pages
171-8
Language
English
Region
Netherlands
NLM ID
9708549
PMCID
PMC1995443
Subset
IM
Grants
NIAID NIH HHS · R01 AI056840 · United States
NIAID NIH HHS · R01 AI056840-02 · United States
External Links
PubMed source DOI: 10.1016/j.parint.2007.04.002 PMC Full Text View journal details
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