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PMID: 9108930 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S. Review

Cell invasion by the vertebrate stages of Plasmodium.

Trends in microbiology ·Vol. 5 ·No. 2 ·1997-02-00 ·Pages 52-8

Sinnis P, Sim BK

Abstract

Protozoans of the genus Plasmodium are the causative agents of malaria; they have a complex life cycle involving vertebrate and arthropod hosts and have three distinct invasive stages. Although the invasive stages probably invade cells using similar mechanisms, each stage has a different host cell specificity and utilizes different receptors to enter cells.

MeSH Terms
Amino Acid Sequence Animals Binding Sites Cell Adhesion Erythrocytes/parasitology Humans Liver/parasitology Malaria/etiology,parasitology Molecular Sequence Data Plasmodium/growth & development,pathogenicity,physiology Protozoan Proteins/genetics,physiology Vertebrates
Chemicals
Protozoan Proteins
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Sinnis P
Dept of Medical and Molecular Parasitology, New York University Medical Center, New York 10016, USA. [email protected]
Sim B K
References (68)
68 references, click to expand
  1. Complete protection against Plasmodium yoelii by adoptive transfer of a CD8+ cytotoxic T-cell clone recognizing sporozoite surface protein 2.
    Infect Immun. 1994 Jul;62(7):2979-83 PMID: 8005684
  2. A reticulocyte-binding protein complex of Plasmodium vivax merozoites.
    Cell. 1992 Jun 26;69(7):1213-26 PMID: 1617731
  3. The origin of parasitophorous vacuole membrane lipids in malaria-infected erythrocytes.
    J Cell Sci. 1993 Sep;106 ( Pt 1):237-48 PMID: 8270628
  4. Red cell membrane protein distribution during malarial invasion.
    J Cell Sci. 1989 Apr;92 ( Pt 4):691-9 PMID: 2532219
  5. Expression of thrombospondin-related anonymous protein in Plasmodium falciparum sporozoites.
    Lancet. 1992 Jun 6;339(8806):1412-3 PMID: 1350818
  6. Cloning of the Plasmodium vivax Duffy receptor.
    Mol Biochem Parasitol. 1991 Jan;44(1):125-32 PMID: 1849231
  7. Immuno-electron microscopic observations on Plasmodium knowlesi sporozoites: localization of protective antigen and its precursors.
    Am J Trop Med Hyg. 1984 Mar;33(2):220-6 PMID: 6711740
  8. Plasmodium falciparum ring-infected erythrocyte surface antigen is released from merozoite dense granules after erythrocyte invasion.
    Infect Immun. 1991 Mar;59(3):1183-7 PMID: 1997422
  9. Analysis of sequence diversity in the Plasmodium falciparum merozoite surface protein-1 (MSP-1).
    Mol Biochem Parasitol. 1993 May;59(1):1-14 PMID: 8515771
  10. The 42-kilodalton rhoptry-associated protein of Plasmodium falciparum.
    Mol Biochem Parasitol. 1992 Jan;50(1):139-49 PMID: 1542308
  11. Remnant lipoproteins inhibit malaria sporozoite invasion of hepatocytes.
    J Exp Med. 1996 Sep 1;184(3):945-54 PMID: 9064354
  12. Structure of the gene encoding the immunodominant surface antigen on the sporozoite of the human malaria parasite Plasmodium falciparum.
    Science. 1984 Aug 10;225(4662):593-9 PMID: 6204383
  13. Kupffer cell elimination enhances development of liver schizonts of Plasmodium berghei in rats.
    Infect Immun. 1993 May;61(5):1936-9 PMID: 8386704
  14. Plasmodium vivax: in vitro growth and reinvasion in red blood cells of Aotus nancymai.
    Exp Parasitol. 1988 Aug;66(2):183-8 PMID: 3294025
  15. Plasmodium vivax interaction with the human Duffy blood group glycoprotein: identification of a parasite receptor-like protein.
    Exp Parasitol. 1989 Nov;69(4):340-50 PMID: 2680568
  16. Interactions of Plasmodium berghei sporozoites and murine Kupffer cells in vitro.
    J Immunol. 1989 Sep 1;143(5):1716-22 PMID: 2668413
  17. Isolation of a Plasmodium falciparum rhoptry protein.
    Mol Biochem Parasitol. 1985 Mar;14(3):293-303 PMID: 3887156
  18. A Plasmodium falciparum antigen that binds to host erythrocytes and merozoites.
    Science. 1985 Nov 1;230(4725):553-6 PMID: 3901257
  19. Localization of CS and non-CS antigens in the sporogonic stages of Plasmodium yoelii.
    Bull World Health Organ. 1990;68 Suppl:165-71 PMID: 2094581
  20. Conservation of the Plasmodium falciparum sporozoite surface protein gene, STARP, in field isolates and distinct species of Plasmodium.
    Mol Biochem Parasitol. 1994 Oct;67(2):255-67 PMID: 7870130
  21. Malarial proteases: assignment of function to activity.
    Res Immunol. 1991 Oct;142(8):672-81 PMID: 1817297
  22. Thrombospondin-related adhesive protein (TRAP) of Plasmodium falciparum: expression during sporozoite ontogeny and binding to human hepatocytes.
    EMBO J. 1995 Aug 15;14(16):3883-94 PMID: 7664729
  23. Malaria circumsporozoite protein binds to heparan sulfate proteoglycans associated with the surface membrane of hepatocytes.
    J Exp Med. 1993 May 1;177(5):1287-98 PMID: 8478608
  24. Characterisation and sequence of a protective rhoptry antigen from Plasmodium falciparum.
    Mol Biochem Parasitol. 1990 Jun;41(1):125-34 PMID: 2200961
  25. Plasmodium sporozoite interactions with macrophages in vitro: a videomicroscopic analysis.
    J Protozool. 1990 Nov-Dec;37(6):528-36 PMID: 2086782
  26. Prepatent periods of a tropical strain of Plasmodium vivax after inoculations of tenfold dilutions of sporozoites.
    Trans R Soc Trop Med Hyg. 1976;70(5-6):482-3 PMID: 320727
  27. Direct infection of hepatocytes by sporozoites of Plasmodium berghei.
    J Protozool. 1982 Aug;29(3):448-54 PMID: 6752394
  28. Host cell invasion by Apicomplexa: an expression of the parasite's contractile system?
    Parasitology. 1983 Oct;87 (Pt 2):199-209 PMID: 6646806
  29. Rationale for the development of an engineered sporozoite malaria vaccine.
    Adv Immunol. 1989;45:283-334 PMID: 2665440
  30. Liver heparan sulfate structure. A novel molecular design.
    J Biol Chem. 1994 Apr 15;269(15):11208-15 PMID: 8157650
  31. Malaria sporozoites and circumsporozoite proteins bind specifically to sulfated glycoconjugates.
    J Cell Biol. 1992 Jun;117(6):1351-7 PMID: 1607393
  32. Structural and functional properties of region II-plus of the malaria circumsporozoite protein.
    J Exp Med. 1994 Jul 1;180(1):297-306 PMID: 8006589
  33. Sialic acid-dependent binding of Plasmodium falciparum merozoite surface antigen, Pf200, to human erythrocytes.
    J Immunol. 1988 Nov 1;141(9):3190-6 PMID: 2459245
  34. Glycophorin B as an EBA-175 independent Plasmodium falciparum receptor of human erythrocytes.
    Mol Biochem Parasitol. 1994 Mar;64(1):55-63 PMID: 8078523
  35. Plasmodium chabaudi p68 serine protease activity required for merozoite entry into mouse erythrocytes.
    Proc Natl Acad Sci U S A. 1992 Oct 15;89(20):9647-51 PMID: 1409678
  36. A malaria sporozoite surface antigen distinct from the circumsporozoite protein.
    Bull World Health Organ. 1990;68 Suppl:152-7 PMID: 2094580
  37. Rapid clearance of malaria circumsporozoite protein (CS) by hepatocytes.
    J Exp Med. 1994 Feb 1;179(2):695-701 PMID: 8294876
  38. The liver sieve: considerations concerning the structure and function of endothelial fenestrae, the sinusoidal wall and the space of Disse.
    Hepatology. 1985 Jul-Aug;5(4):683-92 PMID: 3926620
  39. The basolateral domain of the hepatocyte plasma membrane bears receptors for the circumsporozoite protein of Plasmodium falciparum sporozoites.
    Cell. 1992 Sep 18;70(6):1021-33 PMID: 1326407
  40. Receptor and ligand domains for invasion of erythrocytes by Plasmodium falciparum.
    Science. 1994 Jun 24;264(5167):1941-4 PMID: 8009226
  41. Identification of the erythrocyte binding domains of Plasmodium vivax and Plasmodium knowlesi proteins involved in erythrocyte invasion.
    J Exp Med. 1994 Aug 1;180(2):497-506 PMID: 8046329
  42. Feeding behaviour and sporozoite ejection by infected Anopheles stephensi.
    Trans R Soc Trop Med Hyg. 1991 Mar-Apr;85(2):175-80 PMID: 1887464
  43. Primary structure of a Plasmodium falciparum rhoptry antigen.
    Mol Biochem Parasitol. 1991 Nov;49(1):99-110 PMID: 1775161
  44. Ultrastructural localization of erythrocyte cytoskeletal and integral membrane proteins in Plasmodium falciparum-infected erythrocytes.
    Eur J Cell Biol. 1988 Feb;45(2):192-9 PMID: 2966734
  45. Plasmodium falciparum: analysis of the interaction of antigen Pf155/RESA with the erythrocyte membrane.
    Exp Parasitol. 1991 Jul;73(1):62-72 PMID: 2055301
  46. The proteases and pathogenicity of parasitic protozoa.
    Annu Rev Microbiol. 1993;47:821-53 PMID: 8257117
  47. Primary structure of the 175K Plasmodium falciparum erythrocyte binding antigen and identification of a peptide which elicits antibodies that inhibit malaria merozoite invasion.
    J Cell Biol. 1990 Nov;111(5 Pt 1):1877-84 PMID: 2229177
  48. Thrombospondin related anonymous protein (TRAP) of Plasmodium falciparum binds specifically to sulfated glycoconjugates and to HepG2 hepatoma cells suggesting a role for this molecule in sporozoite invasion of hepatocytes.
    EMBO J. 1993 Jul;12(7):2881-9 PMID: 8392935
  49. An ultrastructural study on the role of Kupffer cells in the process of infection by Plasmodium berghei sporozoites in rats.
    Parasitology. 1983 Apr;86 (Pt 2):231-42 PMID: 6343960
  50. Receptors on red cells for Plasmodium falciparum and their interaction with merozoites.
    Philos Trans R Soc Lond B Biol Sci. 1984 Nov 13;307(1131):189-200 PMID: 6151683
  51. A highly conserved amino-acid sequence in thrombospondin, properdin and in proteins from sporozoites and blood stages of a human malaria parasite.
    Nature. 1988 Sep 1;335(6185):79-82 PMID: 3045563
  52. Evidence for a switching mechanism in the invasion of erythrocytes by Plasmodium falciparum.
    J Clin Invest. 1990 Aug;86(2):618-24 PMID: 2200806
  53. Release of merozoite dense granules during erythrocyte invasion by Plasmodium knowlesi.
    Infect Immun. 1989 Oct;57(10):3230-3 PMID: 2777381
  54. Secretion of Plasmodium falciparum rhoptry protein into the plasma membrane of host erythrocytes.
    J Cell Biol. 1988 May;106(5):1507-13 PMID: 2453514
  55. Cloning and characterization of a novel Plasmodium falciparum sporozoite surface antigen, STARP.
    Mol Biochem Parasitol. 1994 Apr;64(2):219-32 PMID: 7935600
  56. Structure and invasive behaviour of Plasmodium knowlesi merozoites in vitro.
    Parasitology. 1975 Dec;71(3):483-91 PMID: 1202413
  57. Concanavalin A-induced endocytosis in rabbit reticulocytes, and its decrease with reticulocyte maturation.
    J Cell Biol. 1979 Feb;80(2):487-91 PMID: 457755
  58. The ring-infected erythrocyte surface antigen of Plasmodium falciparum associates with spectrin in the erythrocyte membrane.
    Mol Biochem Parasitol. 1991 May;46(1):137-47 PMID: 1852169
  59. Merozoite surface coat precursor protein completely protects Aotus monkeys against Plasmodium falciparum malaria.
    Proc Natl Acad Sci U S A. 1987 May;84(9):3014-8 PMID: 3554251
  60. The Duffy receptor family of Plasmodium knowlesi is located within the micronemes of invasive malaria merozoites.
    Cell. 1990 Oct 5;63(1):141-53 PMID: 2170017
  61. A malaria invasion receptor, the 175-kilodalton erythrocyte binding antigen of Plasmodium falciparum recognizes the terminal Neu5Ac(alpha 2-3)Gal- sequences of glycophorin A.
    J Cell Biol. 1992 Feb;116(4):901-9 PMID: 1310320
  62. A family of erythrocyte binding proteins of malaria parasites.
    Proc Natl Acad Sci U S A. 1992 Aug 1;89(15):7085-9 PMID: 1496004
  63. Characterization of Plasmodium falciparum sporozoite surface protein 2.
    Proc Natl Acad Sci U S A. 1992 Oct 1;89(19):9176-80 PMID: 1409621
  64. Synthetic peptides from the circumsporozoite proteins of Plasmodium falciparum and Plasmodium knowlesi recognize the human hepatoma cell line HepG2-A16 in vitro.
    J Exp Med. 1986 Dec 1;164(6):1915-22 PMID: 3023519
  65. The adhesion of malaria merozoite proteins to erythrocytes: a reflection of function?
    Res Immunol. 1991 Oct;142(8):666-72 PMID: 1817296
  66. Ability of recombinant or native proteins to protect monkeys against heterologous challenge with Plasmodium falciparum.
    Infect Immun. 1991 Oct;59(10):3498-503 PMID: 1894356
  67. A single fragment of a malaria merozoite surface protein remains on the parasite during red cell invasion and is the target of invasion-inhibiting antibodies.
    J Exp Med. 1990 Jul 1;172(1):379-82 PMID: 1694225
  68. Integral membrane protein located in the apical complex of Plasmodium falciparum.
    Mol Cell Biol. 1989 Jul;9(7):3151-4 PMID: 2701947
Article Info
Journal
Trends in microbiology
Abbr.
Trends Microbiol
ISSN
0966-842X
DOI
10.1016/s0966-842x(97)84657-4
Email
[email protected]
Published
1997-02-00
Pages
52-8
Language
English
Region
England
NLM ID
9310916
PMCID
PMC5538855
Subset
IM
Grants
NIAID NIH HHS · K11 AI001175 · United States
NIAID NIH HHS · K11 AI001175-05 · United States
External Links
PubMed source DOI: 10.1016/s0966-842x(97)84657-4 PMC Full Text View journal details
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