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PMID: 1780024 Published · ppublish English Journal Article Review

The structural and functional heterogeneity of glutamic acid decarboxylase: a review.

Neurochemical research ·Vol. 16 ·No. 3 ·1991-03-00 ·Pages 215-26

Erlander MG, Tobin AJ

Abstract

Studies of the GABA-synthetic enzyme glutamate decarboxylase (glutamic acid decarboxylase; GAD; E.C.4.1.1.15) began in 1951 with the work of Roberts and his colleagues. Since then, many investigators have demonstrated the structural and functional heterogeneity of brain GAD. At least part of this heterogeneity derives from the existence of two GAD genes.

MeSH Terms
Animals Brain/enzymology Glutamate Decarboxylase/chemistry,genetics,metabolism Neurons/enzymology,ultrastructure gamma-Aminobutyric Acid/metabolism
Chemicals
gamma-Aminobutyric Acid Glutamate Decarboxylase
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Erlander M G
Neuroscience Program, University of California, Los Angeles 90024.
Tobin A J
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Article Info
Journal
Neurochemical research
Abbr.
Neurochem Res
ISSN
0364-3190
DOI
10.1007/BF00966084
Published
1991-03-00
Pages
215-26
Language
English
Region
United States
NLM ID
7613461
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00966084 View journal details
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