Home LiteratureArticle Details
PMID: 17991679 Published · ppublish English Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

WormBase 2007.

Nucleic acids research ·Vol. 36 ·No. Database issue ·2008-01-00 ·Pages D612-7

Rogers A, Antoshechkin I, Bieri T, Blasiar D, Bastiani C, Canaran P, Chan J, Chen WJ, Davis P, Fernandes J, Fiedler TJ, Han M, Harris TW, Kishore R, Lee R, McKay S, Müller HM, Nakamura C, Ozersky P, Petcherski A, Schindelman G, Schwarz EM, Spooner W, Tuli MA, Van Auken K, Wang D, Wang X, Williams G, Yook K, Durbin R, Stein LD, Spieth J, Sternberg PW

Abstract

WormBase (www.wormbase.org) is the major publicly available database of information about Caenorhabditis elegans, an important system for basic biological and biomedical research. Derived from the initial ACeDB database of C. elegans genetic and sequence information, WormBase now includes the genomic, anatomical and functional information about C. elegans, other Caenorhabditis species and other nematodes. As such, it is a crucial resource not only for C. elegans biologists but the larger biomedical and bioinformatics communities. Coverage of core areas of C. elegans biology will allow the biomedical community to make full use of the results of intensive molecular genetic analysis and functional genomic studies of this organism. Improved search and display tools, wider cross-species comparisons and extended ontologies are some of the features that will help scientists extend their research and take advantage of other nematode species genome sequences.

MeSH Terms
Animals Caenorhabditis elegans/genetics,metabolism Chromosome Mapping Databases, Genetic Gene Expression Gene Regulatory Networks Genes, Helminth Genome, Helminth Genomics Internet Mass Spectrometry Peptides/chemistry Phenotype User-Computer Interface
Chemicals
Peptides
Authors & Affiliations
33 authors, click to expand affiliations / ORCID
Rogers Anthony
Sanger Institute, Wellcome Trust Genome Campus Hinxton, Cambridgeshire CB10 1SA, UK.
Antoshechkin Igor
Bieri Tamberlyn
Blasiar Darin
Bastiani Carol
Canaran Payan
Chan Juancarlos
Chen Wen J
Davis Paul
Fernandes Jolene
Fiedler Tristan J
Han Michael
Harris Todd W
Kishore Ranjana
Lee Raymond
McKay Sheldon
Müller Hans-Michael
Nakamura Cecilia
Ozersky Philip
Petcherski Andrei
Schindelman Gary
Schwarz Erich M
Spooner Will
Tuli Mary Ann
Van Auken Kimberly
Wang Daniel
Wang Xiaodong
Williams Gary
Yook Karen
Durbin Richard
Stein Lincoln D
Spieth John
Sternberg Paul W
References (23)
23 references, click to expand
  1. Comparison of C. elegans and C. briggsae genome sequences reveals extensive conservation of chromosome organization and synteny.
    PLoS Biol. 2007 Jul;5(7):e167 PMID: 17608563
  2. Yeast two-hybrid systems and protein interaction mapping projects for yeast and worm.
    Yeast. 2000 Jun 30;17(2):88-94 PMID: 10900455
  3. Genome-wide prediction of C. elegans genetic interactions.
    Science. 2006 Mar 10;311(5766):1481-4 PMID: 16527984
  4. Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans.
    Cell. 2006 Dec 15;127(6):1193-207 PMID: 17174894
  5. Gene ontology: tool for the unification of biology. The Gene Ontology Consortium.
    Nat Genet. 2000 May;25(1):25-9 PMID: 10802651
  6. Transcriptome profiling of the C. elegans Rb ortholog reveals diverse developmental roles.
    Dev Biol. 2007 May 15;305(2):674-84 PMID: 17368442
  7. OrthoMCL: identification of ortholog groups for eukaryotic genomes.
    Genome Res. 2003 Sep;13(9):2178-89 PMID: 12952885
  8. Inparanoid: a comprehensive database of eukaryotic orthologs.
    Nucleic Acids Res. 2005 Jan 1;33(Database issue):D476-80 PMID: 15608241
  9. Isolation of eight novel Caenorhabditis elegans small RNAs.
    Gene. 2004 Jun 23;335:47-56 PMID: 15194189
  10. WormBook: the online review of Caenorhabditis elegans biology.
    Nucleic Acids Res. 2007 Jan;35(Database issue):D472-5 PMID: 17099225
  11. Textpresso: an ontology-based information retrieval and extraction system for biological literature.
    PLoS Biol. 2004 Nov;2(11):e309 PMID: 15383839
  12. Non-coding RNAs: lessons from the small nuclear and small nucleolar RNAs.
    Nat Rev Mol Cell Biol. 2007 Mar;8(3):209-20 PMID: 17318225
  13. The COG database: an updated version includes eukaryotes.
    BMC Bioinformatics. 2003 Sep 11;4:41 PMID: 12969510
  14. A gateway-compatible yeast one-hybrid system.
    Genome Res. 2004 Oct;14(10B):2093-101 PMID: 15489331
  15. Organization of the Caenorhabditis elegans small non-coding transcriptome: genomic features, biogenesis, and expression.
    Genome Res. 2006 Jan;16(1):20-9 PMID: 16344563
  16. Genes misregulated in C. elegans deficient in Dicer, RDE-4, or RDE-1 are enriched for innate immunity genes.
    RNA. 2007 Jul;13(7):1090-102 PMID: 17526642
  17. Impaired processing of FLP and NLP peptides in carboxypeptidase E (EGL-21)-deficient Caenorhabditis elegans as analyzed by mass spectrometry.
    J Neurochem. 2007 Jul;102(1):246-60 PMID: 17564681
  18. TreeFam: a curated database of phylogenetic trees of animal gene families.
    Nucleic Acids Res. 2006 Jan 1;34(Database issue):D572-80 PMID: 16381935
  19. Decline of nucleotide excision repair capacity in aging Caenorhabditis elegans.
    Genome Biol. 2007;8(5):R70 PMID: 17472752
  20. Yeast three-hybrid system to detect and analyze RNA-protein interactions.
    Methods Enzymol. 2000;318:399-419 PMID: 10890002
  21. The Ensembl analysis pipeline.
    Genome Res. 2004 May;14(5):934-41 PMID: 15123589
  22. Ensembl 2007.
    Nucleic Acids Res. 2007 Jan;35(Database issue):D610-7 PMID: 17148474
  23. Evolution of small nucleolar RNAs in nematodes.
    Nucleic Acids Res. 2006 May 19;34(9):2676-85 PMID: 16714446
Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
1362-4962
Published
2008-01-00
Epub
2007-00-08
Pages
D612-7
Language
English
Region
England
NLM ID
0411011
PMCID
PMC2238927
Subset
IM
Grants
Medical Research Council · G0701197 · United Kingdom
NHGRI NIH HHS · P41 HG002223 · United States
NHGRI NIH HHS · P41-HG02223 · United States
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]