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PMID: 17991680 Published · ppublish English Journal Article Research Support, N.I.H., Extramural

The Zebrafish Information Network: the zebrafish model organism database provides expanded support for genotypes and phenotypes.

Nucleic acids research ·Vol. 36 ·No. Database issue ·2008-01-00 ·Pages D768-72

Sprague J, Bayraktaroglu L, Bradford Y, Conlin T, Dunn N, Fashena D, Frazer K, Haendel M, Howe DG, Knight J, Mani P, Moxon SA, Pich C, Ramachandran S, Schaper K, Segerdell E, Shao X, Singer A, Song P, Sprunger B, Van Slyke CE, Westerfield M

Abstract

The Zebrafish Information Network (ZFIN, http://zfin.org), the model organism database for zebrafish, provides the central location for curated zebrafish genetic, genomic and developmental data. Extensive data integration of mutant phenotypes, genes, expression patterns, sequences, genetic markers, morpholinos, map positions, publications and community resources facilitates the use of the zebrafish as a model for studying gene function, development, behavior and disease. Access to ZFIN data is provided via web-based query forms and through bulk data files. ZFIN is the definitive source for zebrafish gene and allele nomenclature, the zebrafish anatomical ontology (AO) and for zebrafish gene ontology (GO) annotations. ZFIN plays an active role in the development of cross-species ontologies such as the phenotypic quality ontology (PATO) and the gene ontology (GO). Recent enhancements to ZFIN include (i) a new home page and navigation bar, (ii) expanded support for genotypes and phenotypes, (iii) comprehensive phenotype annotations based on anatomical, phenotypic quality and gene ontologies, (iv) a BLAST server tightly integrated with the ZFIN database via ZFIN-specific datasets, (v) a global site search and (vi) help with hands-on resources.

MeSH Terms
Animals Databases, Genetic Genotype Internet Models, Animal Mutation Phenotype Sequence Alignment Systems Integration User-Computer Interface Zebrafish/anatomy & histology,genetics
Authors & Affiliations
22 authors, click to expand affiliations / ORCID
Sprague Judy
The Zebrafish Information Network, 5291 University of Oregon, Eugene, OR 97403-5291, USA. [email protected]
Bayraktaroglu Leyla
Bradford Yvonne
Conlin Tom
Dunn Nathan
Fashena David
Frazer Ken
Haendel Melissa
Howe Douglas G
Knight Jonathan
Mani Prita
Moxon Sierra A T
Pich Christian
Ramachandran Sridhar
Schaper Kevin
Segerdell Erik
Shao Xiang
Singer Amy
Song Peiran
Sprunger Brock
Van Slyke Ceri E
Westerfield Monte
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8 references, click to expand
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Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
1362-4962
Published
2008-01-00
Epub
2007-00-08
Pages
D768-72
Language
English
Region
England
NLM ID
0411011
PMCID
PMC2238839
Subset
IM
Grants
NHGRI NIH HHS · P41 HG002659 · United States
NHGRI NIH HHS · HG004028 · United States
NHGRI NIH HHS · U54 HG004028 · United States
NHGRI NIH HHS · HG002659 · United States
NHGRI NIH HHS · U41 HG002659 · United States
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