Abstract
The expanding number of members in the various human heat shock protein (HSP) families and the inconsistencies in their nomenclature have often led to confusion. Here, we propose new guidelines for the nomenclature of the human HSP families, HSPH (HSP110), HSPC (HSP90), HSPA (HSP70), DNAJ (HSP40), and HSPB (small HSP) as well as for the human chaperonin families HSPD/E (HSP60/HSP10) and CCT (TRiC). The nomenclature is based largely on the more consistent nomenclature assigned by the HUGO Gene Nomenclature Committee and used in the National Center of Biotechnology Information Entrez Gene database for the heat shock genes. In addition to this nomenclature, we provide a list of the human Entrez Gene IDs and the corresponding Entrez Gene IDs for the mouse orthologs.
MeSH Terms
Animals
Chaperonins/classification,genetics
HSP110 Heat-Shock Proteins/classification
HSP40 Heat-Shock Proteins/classification
HSP70 Heat-Shock Proteins/classification
HSP90 Heat-Shock Proteins/classification
Heat-Shock Proteins/classification
Heat-Shock Proteins, Small/classification
Humans
Mice
Molecular Chaperones/classification,genetics
Terminology as Topic
Chemicals
HSP110 Heat-Shock Proteins
HSP40 Heat-Shock Proteins
HSP70 Heat-Shock Proteins
HSP90 Heat-Shock Proteins
Heat-Shock Proteins
Heat-Shock Proteins, Small
Molecular Chaperones
Chaperonins
Authors & Affiliations
9 authors, click to expand affiliations / ORCID
Kampinga Harm H
Department of Cell Biology, Section of Radiation and Stress Cell Biology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
[email protected]
Hageman Jurre
Vos Michel J
Kubota Hiroshi
Tanguay Robert M
Bruford Elspeth A
Cheetham Michael E
Chen Bin
Hightower Lawrence E
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