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PMID: 1879486 Published · ppublish English Journal Article

Genetic diversity among toxigenic and nontoxigenic Vibrio cholerae O1 isolated from the Western Hemisphere.

Epidemiology and infection ·Vol. 107 ·No. 1 ·1991-08-00 ·Pages 225-33

Chen F, Evins GM, Cook WL, Almeida R, Hargrett-Bean N, Wachsmuth K

Abstract

Multilocus enzyme electrophoresis was used to examine genetic relationships among and between toxigenic and non-toxigenic isolates of Vibrio cholerae O1 obtained from patients and the environment in the US Gulf Coast and surrounding areas. A total of 23 toxigenic and 23 non-toxigenic strains were examined. All the toxigenic and 7 of the non-toxigenic strains had the same alleles at 16 enzyme loci, whereas the balance of the nontoxigenic strains had 9 distinct combinations of alleles. This study suggests that all of the toxigenic strains belong to a single clone, and that while some of the non-toxigenic isolates were related, most were of diverse origin.

MeSH Terms
Alleles Brazil Cholera/microbiology Cholera Toxin/biosynthesis Cluster Analysis Electrophoresis, Starch Gel Environmental Microbiology Enzymes/analysis,genetics Genetic Variation Genotype Humans Mexico Peru United States Vibrio cholerae/genetics,isolation & purification,metabolism
Chemicals
Enzymes Cholera Toxin
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
Chen F
Laboratory for Microbial and Biochemical Sciences, Georgia State University, Atlanta 30303.
Evins G M
Cook W L
Almeida R
Hargrett-Bean N
Wachsmuth K
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Article Info
Journal
Epidemiology and infection
Abbr.
Epidemiol Infect
ISSN
0950-2688
DOI
10.1017/s0950268800048846
Published
1991-08-00
Pages
225-33
Language
English
Region
England
NLM ID
8703737
PMCID
PMC2272037
Subset
IM
External Links
PubMed source DOI: 10.1017/s0950268800048846 PMC Full Text View journal details
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