Glutamine utilization in both the arginine-specific and pyrimidine-specific carbamoyl phosphate synthase enzymes of eurospora crassa.

Molecular & general genetics : MGG ·Vol. 149 ·No. 2 ·1976-12-08 ·Pages 175-8

Makoff AJ, Radford A

Abstract

As glutamine-dependent carbamoyl phasphate synthetase (CPS) activity in some organisms is composed of a glutaminase and an ammonium-dependent CPS, CPS- mutants in Neurospora crassa were examined for glutamine- and ammonium-dependent CPS activities. No evidence was found that the genetic location of these two functions were separable. This is discussed with reference to the close genetic proximity of the CPSpyr and aspartate carbamoyltransferase (ACT) structural gene (pyr-3) and the arg-2 gene which appears to specify a subunit responsible for glutamine utilisation in CPSarg.

MeSH Terms

Genes Genetic Linkage Glutamine/metabolism Neurospora/enzymology Neurospora crassa/enzymology Phosphotransferases/metabolism

Chemicals

Glutamine Phosphotransferases

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Makoff A J

Radford A

References (14)

14 references, click to expand

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Article Info

Journal

Molecular & general genetics : MGG

Abbr.

Mol Gen Genet

ISSN

0026-8925

DOI

10.1007/BF00332886

Published

1976-12-08

Pages

175-8

Language

English

Region

Germany

NLM ID

0125036

Subset

External Links

PubMed source DOI: 10.1007/BF00332886

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Glutamine utilization in both the arginine-specific and pyrimidine-specific carbamoyl phosphate synthase enzymes of eurospora crassa.

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