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A molecular switch that controls cell spreading and retraction.
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Nat Rev Mol Cell Biol. 2005 Jan;6(1):56-68
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Analysis of Fyn function in hemostasis and alphaIIbbeta3-integrin signaling.
J Cell Sci. 2008 May 15;121(Pt 10):1641-8
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J Cell Sci. 2008 May 1;121(Pt 9):1345-7
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Nat Cell Biol. 2006 Jun;8(6):601-6
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Trends Cell Biol. 2008 Jun;18(6):257-63
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Complexes of tetraspanins with integrins: more than meets the eye.
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Substrate rigidity and force define form through tyrosine phosphatase and kinase pathways.
Trends Cell Biol. 2006 Apr;16(4):213-23
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Integrin-linked kinase: a cancer therapeutic target unique among its ILK.
Nat Rev Cancer. 2005 Jan;5(1):51-63
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J Cell Sci. 2006 Oct 1;119(Pt 19):3901-3
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Structural basis for the autoinhibition of talin in regulating integrin activation.
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The molecular basis of filamin binding to integrins and competition with talin.
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Cell adaptive response to extracellular matrix density is controlled by ICAP-1-dependent beta1-integrin affinity.
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Paxillin comes of age.
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Kindlin-2 controls bidirectional signaling of integrins.
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The Kindler syndrome protein is regulated by transforming growth factor-beta and involved in integrin-mediated adhesion.
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Functional atlas of the integrin adhesome.
Nat Cell Biol. 2007 Aug;9(8):858-67
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Talin binding to integrin beta tails: a final common step in integrin activation.
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Synergistic control of cell adhesion by integrins and syndecans.
Nat Rev Mol Cell Biol. 2007 Dec;8(12):957-69
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New approaches to blockade of alpha4-integrins, proven therapeutic targets in chronic inflammation.
Biochem Pharmacol. 2006 Nov 30;72(11):1460-8
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Integrin beta cytoplasmic domain interactions with phosphotyrosine-binding domains: a structural prototype for diversity in integrin signaling.
Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2272-7
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Structure of the integrin alphaIIb transmembrane segment.
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Sensing the environment: a historical perspective on integrin signal transduction.
Nat Cell Biol. 2002 Apr;4(4):E83-90
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C. elegans PAT-4/ILK functions as an adaptor protein within integrin adhesion complexes.
Curr Biol. 2002 May 14;12(10):787-97
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Probing the integrin-actin linkage using high-resolution protein velocity mapping.
J Cell Sci. 2006 Dec 15;119(Pt 24):5204-14
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Integrins and actin filaments: reciprocal regulation of cell adhesion and signaling.
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The structure and regulation of vinculin.
Trends Cell Biol. 2006 Sep;16(9):453-60
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Structural basis of integrin regulation and signaling.
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Structural basis of integrin activation by talin.
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The antithrombotic potential of selective blockade of talin-dependent integrin alpha IIb beta 3 (platelet GPIIb-IIIa) activation.
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A dual role for integrin-linked kinase in platelets: regulating integrin function and alpha-granule secretion.
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Src kinase activation by direct interaction with the integrin beta cytoplasmic domain.
Proc Natl Acad Sci U S A. 2003 Nov 11;100(23):13298-302
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