Immunoglobulin synthesis by an SV-40-induced hamster lymphoma.

Immunology ·Vol. 31 ·No. 3 ·1976-09-00 ·Pages 495-502

Coe JE

Abstract

A transplantable lymphoid tumour induced in Syrian hamsters by SV-40 was shown to synthesize a 7Sgamma2 monoclonal immunoglobulin of the same idiotype was also found in the membrane of the tumour cell. The induction of immunoglobulin synthesizing tumours by SV-40 should be useful for studies on immunoglobulin synthesis, lymphoid cell receptors and tumour immunity.

MeSH Terms

Animals Cell Membrane/immunology Cricetinae Immunodiffusion Immunoglobulins/biosynthesis Lymphoma/immunology Neoplasms, Experimental/immunology Simian virus 40

Chemicals

Immunoglobulins

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Coe J E

References (20)

20 references, click to expand

Serum-protein abnormality in a transplantable plasmacytoma of the Syrian golden hamster.
J Natl Cancer Inst. 1962 May;28:1193-205 PMID: 13881651
TESTS IN HAMSTERS FOR ONCOGENIC QUALITY OF ORDINARY VIRUSES INCLUDING ADENOVIRUS TYPE 7.
Proc Soc Exp Biol Med. 1964 Apr;115:1141-50 PMID: 14166581
B-cell origin of hamster lymphoid tumors induced by simian virus 40.
J Natl Cancer Inst. 1975 Jan;54(1):269-70 PMID: 163322
Common individual antigenic determinants in five of eight BALB-c IgA myeloma proteins that bind phosphoryl choline.
J Exp Med. 1970 Oct 1;132(4):737-51 PMID: 4101363
The inheritance of individual antigenic specificities of rabbit antibodies to streptococcal carbohydrates.
J Exp Med. 1971 Aug 1;134(2):532-52 PMID: 4104426
Myeloma proteins as tumor-specific transplantation antigens.
Proc Natl Acad Sci U S A. 1972 Jun;69(6):1540-4 PMID: 4113870
Idiotypic determinants of immunoglobulin M detected on the surface of human lymphocytes by cytotoxicity assays.
J Exp Med. 1972 Sep 1;136(3):650-5 PMID: 4115135
Genetics of a new IgVH (T15 idiotype) marker in the mouse regulating natural antibody to phosphorylcholine.
J Exp Med. 1974 Apr 1;139(4):983-1001 PMID: 4131516
Protective and cellular immune responses to idiotypic determinants on cells from a spontaneous lymphoma of NZB-NZW F1 mice.
J Exp Med. 1974 Dec 1;140(6):1547-58 PMID: 4139232
A method of trace iodination of proteins for immunologic studies.
Int Arch Allergy Appl Immunol. 1966;29(2):185-9 PMID: 4160044
Immune response in the hamster. VI. Antibody response in polyoma oncogenesis.
J Natl Cancer Inst. 1972 Jul;49(1):39-44 PMID: 4338780
Induction of lymphocytic leukemia, lymphosarcoma, reticulum cell sarcoma, and osteogenic sarcoma in the Syrian golden hamster by oncogenic DNA simian virus 40.
J Natl Cancer Inst. 1973 May;50(5):1347-65 PMID: 4351397
Specific suppression of the antibody response by antibodies to receptors.
Proc Natl Acad Sci U S A. 1972 Sep;69(9):2701-5 PMID: 4403565
An ultrastructural study of lymphocytes with surface-bound immunoglobulin.
J Exp Med. 1972 Feb 1;135(2):267-76 PMID: 4536751
Suppression of immunoglobulin class synthesis in mice. I. Effects of treatment with antibody to -chain.
J Exp Med. 1972 Feb 1;135(2):277-97 PMID: 4551216
Detection of idiotypic cross-reactions among streptococcal antisera from related rabbits.
J Exp Med. 1973 Sep 1;138(3):522-37 PMID: 4727913
Immunoglobulins as cell receptors.
Ann N Y Acad Sci. 1971 Dec 31;190:420-31 PMID: 4944965
Synthesis of immunoglobulins by biopsied tissues and cell lines from Burkitt's lymphoma.
Immunology. 1972 May;22(5):847-57 PMID: 5021706
Synthesis of plasma membrane-associated and secretory immunoglobulin in diploid lymphocytes.
J Exp Med. 1972 Jan;135(1):136-49 PMID: 5061901
Protein purification by affinity chromatography. Derivatizations of agarose and polyacrylamide beads.
J Biol Chem. 1970 Jun;245(12):3059-65 PMID: 5432796

Article Info

Journal

Immunology

Abbr.

Immunology

ISSN

0019-2805

Published

1976-09-00

Pages

495-502

Language

English

Region

England

NLM ID

0374672

PMCID

PMC1445237

Subset

External Links

PubMed source PMC Full Text View journal details

Analysis Services

Immunoglobulin synthesis by an SV-40-induced hamster lymphoma.

Contact

WeChat Official Account