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PMID: 19490890 Published · ppublish English Journal Article Research Support, N.I.H., Extramural Review

At loose ends: resecting a double-strand break.

Cell ·Vol. 137 ·No. 5 ·2009-05-29 ·Pages 807-10

Bernstein KA, Rothstein R

Abstract

Double-strand break (DSB) repair is critical for maintaining genomic integrity and requires the processing of the 5' DSB ends. Recent studies have shed light on the mechanism and regulation of DNA end processing during DSB repair by homologous recombination.

MeSH Terms
Animals Archaea/metabolism Cell Cycle DNA Breaks, Double-Stranded DNA Repair Humans
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Bernstein Kara A
Columbia University Medical Center, Department of Genetics & Development, New York, NY 10032, USA.
Rothstein Rodney
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Article Info
Journal
Cell
Abbr.
Cell
ISSN
1097-4172
DOI
10.1016/j.cell.2009.05.007
Published
2009-05-29
Pages
807-10
Language
English
Region
United States
NLM ID
0413066
PMCID
PMC3977653
Subset
IM
Grants
NIGMS NIH HHS · GM67055 · United States
NIGMS NIH HHS · R37 GM050237 · United States
NIGMS NIH HHS · R01 GM067055 · United States
NIGMS NIH HHS · R01 GM050237 · United States
NIGMS NIH HHS · GM50237 · United States
NIGMS NIH HHS · F32 GM078840 · United States
NIGMS NIH HHS · GM078840 · United States
External Links
PubMed source DOI: 10.1016/j.cell.2009.05.007 PMC Full Text View journal details
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