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PMID: 19850722 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S.

GeMInA, Genomic Metadata for Infectious Agents, a geospatial surveillance pathogen database.

Nucleic acids research ·Vol. 38 ·No. Database issue ·2010-01-00 ·Pages D754-64

Schriml LM, Arze C, Nadendla S, Ganapathy A, Felix V, Mahurkar A, Phillippy K, Gussman A, Angiuoli S, Ghedin E, White O, Hall N

Abstract

The Gemina system (http://gemina.igs.umaryland.edu) identifies, standardizes and integrates the outbreak metadata for the breadth of NIAID category A-C viral and bacterial pathogens, thereby providing an investigative and surveillance tool describing the Who [Host], What [Disease, Symptom], When [Date], Where [Location] and How [Pathogen, Environmental Source, Reservoir, Transmission Method] for each pathogen. The Gemina database will provide a greater understanding of the interactions of viral and bacterial pathogens with their hosts and infectious diseases through in-depth literature text-mining, integrated outbreak metadata, outbreak surveillance tools, extensive ontology development, metadata curation and representative genomic sequence identification and standards development. The Gemina web interface provides metadata selection and retrieval of a pathogen's; Infection Systems (Pathogen, Host, Disease, Transmission Method and Anatomy) and Incidents (Location and Date) along with a hosts Age and Gender. The Gemina system provides an integrated investigative and geospatial surveillance system connecting pathogens, pathogen products and disease anchored on the taxonomic ID of the pathogen and host to identify the breadth of hosts and diseases known for these pathogens, to identify the extent of outbreak locations, and to identify unique genomic regions with the DNA Signature Insignia Detection Tool.

MeSH Terms
Animals Bacterial Infections/microbiology Communicable Diseases/microbiology,virology Computational Biology/methods,trends Databases, Factual Databases, Genetic Databases, Nucleic Acid Genes, Bacterial Genes, Viral Humans Information Storage and Retrieval/methods Internet Software User-Computer Interface Virus Diseases/virology
Authors & Affiliations
12 authors, click to expand affiliations / ORCID
Schriml Lynn M
Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA. [email protected]
Arze Cesar
Nadendla Suvarna
Ganapathy Anu
Felix Victor
Mahurkar Anup
Phillippy Katherine
Gussman Aaron
Angiuoli Sam
Ghedin Elodie
White Owen
Hall Neil
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8 references, click to expand
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Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
1362-4962
Published
2010-01-00
Epub
2009-00-22
Pages
D754-64
Language
English
Region
England
NLM ID
0411011
PMCID
PMC2808878
Subset
IM
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