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PMID: 20734094 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Review

From signal transduction to autophagy of plant cell organelles: lessons from yeast and mammals and plant-specific features.

Protoplasma ·Vol. 247 ·No. 3-4 ·2010-12-00 ·Pages 233-56

Reumann S, Voitsekhovskaja O, Lillo C

Abstract

Autophagy is an evolutionarily conserved intracellular process for the vacuolar degradation of cytoplasmic constituents. The central structures of this pathway are newly formed double-membrane vesicles (autophagosomes) that deliver excess or damaged cell components into the vacuole or lysosome for proteolytic degradation and monomer recycling. Cellular remodeling by autophagy allows organisms to survive extensive phases of nutrient starvation and exposure to abiotic and biotic stress. Autophagy was initially studied by electron microscopy in diverse organisms, followed by molecular and genetic analyses first in yeast and subsequently in mammals and plants. Experimental data demonstrate that the basic principles, mechanisms, and components characterized in yeast are conserved in mammals and plants to a large extent. However, distinct autophagy pathways appear to differ between kingdoms. Even though direct information remains scarce particularly for plants, the picture is emerging that the signal transduction cascades triggering autophagy and the mechanisms of organelle turnover evolved further in higher eukaryotes for optimization of nutrient recycling. Here, we summarize new research data on nitrogen starvation-induced signal transduction and organelle autophagy and integrate this knowledge into plant physiology.

MeSH Terms
Animals Autophagy Biological Evolution Chloroplasts/physiology Humans Mammals Nitrogen/physiology Organelles/physiology Peroxisomes/physiology Plant Physiological Phenomena Plants/metabolism,ultrastructure Signal Transduction Yeasts/physiology,ultrastructure
Chemicals
Nitrogen
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Reumann Sigrun
Centre for Organelle Research, University of Stavanger, 4021 Stavanger, Norway. [email protected]
Voitsekhovskaja Olga
Lillo Cathrine
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Article Info
Journal
Protoplasma
Abbr.
Protoplasma
ISSN
1615-6102
DOI
10.1007/s00709-010-0190-0
Email
[email protected]
Published
2010-12-00
Epub
2010-00-24
Pages
233-56
Language
English
Region
Austria
NLM ID
9806853
Subset
IM
External Links
PubMed source DOI: 10.1007/s00709-010-0190-0 View journal details
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