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PMID: 21144126 Published · ppublish English Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S.

MADS-box genes of maize: frequent targets of selection during domestication.

Genetics research ·Vol. 93 ·No. 1 ·2011-02-00 ·Pages 65-75

Zhao Q, Weber AL, McMullen MD, Guill K, Doebley J

Abstract

MADS-box genes encode transcription factors that are key regulators of plant inflorescence and flower development. We examined DNA sequence variation in 32 maize MADS-box genes and 32 randomly chosen maize loci and investigated their involvement in maize domestication and improvement. Using neutrality tests and a test based on coalescent simulation of a bottleneck model, we identified eight MADS-box genes as putative targets of the artificial selection associated with domestication. According to neutrality tests, one additional MADS-box gene appears to have been under selection during modern agricultural improvement of maize. For random loci, two genes were indicated as targets of selection during domestication and four additional genes were indicated to be candidate-selected loci for maize improvement. These results suggest that MADS-box genes were more frequent targets of selection during domestication than genes chosen at random from the genome.

MeSH Terms
Genes, Plant Genetic Variation Genome, Plant Plant Proteins/genetics,metabolism Selection, Genetic/genetics Transcription Factors/genetics,metabolism Zea mays/genetics,metabolism
Chemicals
Plant Proteins Transcription Factors
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Zhao Qiong
Laboratory of Genetics, University of Wisconsin-Madison, Madison, WI 53706, USA.
Weber Allison L
McMullen Michael D
Guill Katherine
Doebley John
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Article Info
Journal
Genetics research
Abbr.
Genet Res (Camb)
ISSN
1469-5073
DOI
10.1017/S0016672310000509
Published
2011-02-00
Epub
2010-00-14
Pages
65-75
Language
English
Region
England
NLM ID
101550220
PMCID
PMC3474543
Subset
IM
Grants
NIGMS NIH HHS · T32 GM007133-25 · United States
NIGMS NIH HHS · T32 GM007133 · United States
NIGMS NIH HHS · T32 GM007133-27 · United States
NIGMS NIH HHS · R01 GM058816 · United States
NIGMS NIH HHS · T32 GM007133-24 · United States
NIGMS NIH HHS · T32 GM007133-26 · United States
External Links
PubMed source DOI: 10.1017/S0016672310000509 PMC Full Text View journal details
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