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PMID: 21307954 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Comparative metagenomics of microbial traits within oceanic viral communities.

The ISME journal ·Vol. 5 ·No. 7 ·2011-07-00 ·Pages 1178-90

Sharon I, Battchikova N, Aro EM, Giglione C, Meinnel T, Glaser F, Pinter RY, Breitbart M, Rohwer F, Béjà O

Abstract

Viral genomes often contain genes recently acquired from microbes. In some cases (for example, psbA) the proteins encoded by these genes have been shown to be important for viral replication. In this study, using a unique search strategy on the Global Ocean Survey (GOS) metagenomes in combination with marine virome and microbiome pyrosequencing-based datasets, we characterize previously undetected microbial metabolic capabilities concealed within the genomes of uncultured marine viral communities. A total of 34 microbial gene families were detected on 452 viral GOS scaffolds. The majority of auxiliary metabolic genes found on these scaffolds have never been reported in phages. Host genes detected in viruses were mainly divided between genes encoding for different energy metabolism pathways, such as electron transport and newly identified photosystem genes, or translation and post-translation mechanism related. Our findings suggest previously undetected ways, in which marine phages adapt to their hosts and improve their fitness, including translation and post-translation level control over the host rather than the already known transcription level control.

MeSH Terms
Bacteriophages/genetics Cluster Analysis Genes, Viral Genome, Viral Metagenome Metagenomics Oceans and Seas Phylogeny Seawater/virology Sequence Analysis, DNA Water Microbiology
Authors & Affiliations
10 authors, click to expand affiliations / ORCID
Sharon Itai
Faculty of Biology, Technion, Israel Institute of Technology, Haifa, Israel.
Battchikova Natalia
Aro Eva-Mari
Giglione Carmela
Meinnel Thierry
Glaser Fabian
Pinter Ron Y
Breitbart Mya
Rohwer Forest
Béjà Oded
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Article Info
Journal
The ISME journal
Abbr.
ISME J
ISSN
1751-7370
DOI
10.1038/ismej.2011.2
Published
2011-07-00
Epub
2011-00-10
Pages
1178-90
Language
English
Region
England
NLM ID
101301086
PMCID
PMC3146289
Subset
IM
External Links
PubMed source DOI: 10.1038/ismej.2011.2 PMC Full Text View journal details
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