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PMID: 214513 Published · ppublish English Journal Article

Specific adsorption of H-2-restricted cytotoxi T cells to macrophage monolayers.

The Journal of experimental medicine ·Vol. 148 ·No. 6 ·1978-12-01 ·Pages 1711-5

Kees U, Müllbacher A, Blanden RV

Abstract

These experiments tested whether Tc cells specific for foreign antigen (X) plus self H-2 adsorbed to macrophage monolayers displaying (a) X with allogeneic H-2; (B) self H-2 alone; (c) X plus self H-2. Specific adsorption occurred only in case (c), a result compatible with altered self and requiring further operational assumptions in dual recognition models.

MeSH Terms
Animals Binding Sites Cell Adhesion Cytotoxicity, Immunologic H-2 Antigens Influenza A virus/immunology Macrophages/immunology Mice Parainfluenza Virus 1, Human/immunology T-Lymphocytes/immunology Trinitrobenzenes/immunology
Chemicals
H-2 Antigens Trinitrobenzenes
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Kees U
Müllbacher A
Blanden R V
References (21)
21 references, click to expand
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Article Info
Journal
The Journal of experimental medicine
Abbr.
J Exp Med
ISSN
0022-1007
DOI
10.1084/jem.148.6.1711
Published
1978-12-01
Pages
1711-5
Language
English
Region
United States
NLM ID
2985109R
PMCID
PMC2185098
Subset
IM
External Links
PubMed source DOI: 10.1084/jem.148.6.1711 PMC Full Text View journal details
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