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PMID: 22293552 Published · epublish English Journal Article Research Support, American Recovery and Reinvestment Act Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S.

Uberon, an integrative multi-species anatomy ontology.

Genome biology ·Vol. 13 ·No. 1 ·2012-01-31 ·Pages R5

Mungall CJ, Torniai C, Gkoutos GV, Lewis SE, Haendel MA

Abstract

We present Uberon, an integrated cross-species ontology consisting of over 6,500 classes representing a variety of anatomical entities, organized according to traditional anatomical classification criteria. The ontology represents structures in a species-neutral way and includes extensive associations to existing species-centric anatomical ontologies, allowing integration of model organism and human data. Uberon provides a necessary bridge between anatomical structures in different taxa for cross-species inference. It uses novel methods for representing taxonomic variation, and has proved to be essential for translational phenotype analyses. Uberon is available at http://uberon.org.

MeSH Terms
Anatomy, Comparative Classification Computational Biology Databases, Factual Humans Phenotype Software Species Specificity
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Mungall Christopher J
Genomics Division, Lawrence Berkeley National Laboratory, 1 Cycltotron Road MS 64-121, Berkeley, CA 94720, USA. [email protected]
Torniai Carlo
Gkoutos Georgios V
Lewis Suzanna E
Haendel Melissa A
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Article Info
Journal
Genome biology
Abbr.
Genome Biol
ISSN
1474-760X
DOI
10.1186/gb-2012-13-1-r5
Email
[email protected]
Published
2012-01-31
Epub
2012-00-31
Pages
R5
Language
English
Region
England
NLM ID
100960660
PMCID
PMC3334586
Subset
IM
Grants
NCRR NIH HHS · 1U24RR029825-01 · United States
NHGRI NIH HHS · U41 HG002273 · United States
NHGRI NIH HHS · P41HG002273 · United States
NHGRI NIH HHS · 5R01HG004838 · United States
NHGRI NIH HHS · R01 HG004838 · United States
NHGRI NIH HHS · P41HG002273-09S1 · United States
External Links
PubMed source DOI: 10.1186/gb-2012-13-1-r5 PMC Full Text View journal details
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