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PMID: 225552 Published · ppublish English Journal Article

Nucleotide sequence of the self-priming 3' terminus of the single-stranded DNA extracted from the parvovirus Kilham rat virus.

Journal of virology ·Vol. 30 ·No. 3 ·1979-06-00 ·Pages 946-50

Salzman LA, Fabisch P

Abstract

The parvovirus genome is a linear, single-stranded DNA molecule with double-stranded hairpin termini. The 3' terminus can serve in vitro as a self-primer for the synthesis of a double-stranded viral DNA intermediate. We have sequenced the nucleotides in the 3' terminus and propose a model for the secondary structure of the terminus and the in vitro origin of replication for the complementary viral DNA strand.

MeSH Terms
Base Sequence Coliphages/enzymology DNA, Single-Stranded/analysis DNA, Viral/analysis DNA-Directed DNA Polymerase/metabolism Nucleotides/analysis Parvoviridae/analysis Parvovirus/analysis
Chemicals
DNA, Single-Stranded DNA, Viral Nucleotides DNA-Directed DNA Polymerase
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Salzman L A
Fabisch P
References (16)
16 references, click to expand
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Article Info
Journal
Journal of virology
Abbr.
J Virol
ISSN
0022-538X
Published
1979-06-00
Pages
946-50
Language
English
Region
United States
NLM ID
0113724
PMCID
PMC353409
Subset
IM
Databases
GENBANK
M10643
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