A non-Mendelian factor, [eta(+)], causes lethality of yeast omnipotent-suppressor strains.

Current genetics ·Vol. 8 ·No. 8 ·1984-10-00 ·Pages 567-73

Liebman SW, All-Robyn JA

Abstract

Omnipotent suppressors cause translational ambiguity and have been associated with poor growth and inviability. We now report that a non-Mendelian element, [eta(+)], causes this inviability. In [eta(-)] strains the suppressors are not inviable. The [eta(+)] genetic element segregates to about 70% of the meiotic progeny, although almost all of the spores probably have the [eta(+)] phenotype for the first few divisions. Growth on 5 mM guanidine hydrochloride efficiently causes [eta(+)] strains to become [eta(-)]. The [eta(+)] factor has many similarities with the previously described [psi(+)] factor (Cox 1965, 1971). However, [eta(+)] and [psi(+)] differ in their patterns of inheritance, and by the fact that [psi(+)] affects ochre specific and not omnipotent suppressors, while the converse is true of [eta(+)].

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Liebman S W

Department of Biological Sciences, University of Illinois at Chicago, Box 4348, 60680, Chicago, Illinois, USA.

All-Robyn J A

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Article Info

Journal

Current genetics

Abbr.

Curr Genet

ISSN

0172-8083

DOI

10.1007/BF00395701

Published

1984-10-00

Pages

567-73

Language

English

Region

United States

NLM ID

8004904

External Links

PubMed source DOI: 10.1007/BF00395701 View journal details

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A non-Mendelian factor, [eta(+)], causes lethality of yeast omnipotent-suppressor strains.

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