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PMID: 2417940 Published · ppublish English Journal Article Review

Class I genes and molecules: an update.

Immunology ·Vol. 57 ·No. 1 ·1986-01-00 ·Pages 3-18

Lew AM, Lillehoj EP, Cowan EP, Maloy WL, van Schravendijk MR, Coligan JE

Abstract

暂无摘要

MeSH Terms
Amino Acid Sequence Animals Base Sequence Cell Transformation, Viral Chromosome Mapping Epitopes/immunology Gene Conversion Gene Expression Regulation Genes, MHC Class II Genetic Variation Humans Major Histocompatibility Complex Mice Mice, Inbred BALB C Mice, Inbred C57BL Mutation Oncogenic Viruses/pathogenicity Polymorphism, Genetic Protein Biosynthesis RNA Splicing T-Lymphocytes, Cytotoxic/immunology
Chemicals
Epitopes
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
Lew A M
Lillehoj E P
Cowan E P
Maloy W L
van Schravendijk M R
Coligan J E
References (112)
112 references, click to expand
  1. A molecular hybrid of the H-2Dd and H-2Ld genes expressed in the dm1 mutant.
    Proc Natl Acad Sci U S A. 1984 Aug;81(16):5204-8 PMID: 6206494
  2. Biochemical and cellular identification of HLA-Bw44 subtypes.
    Hum Immunol. 1984 Oct;11(2):69-76 PMID: 6333415
  3. Rejection of transplantable AKR leukaemia cells following MHC DNA-mediated cell transformation.
    Nature. 1984 Oct 25-31;311(5988):750-2 PMID: 6333639
  4. Mouse histocompatibility genes: structure and organisation of a Kd gene.
    EMBO J. 1983;2(2):245-54 PMID: 11894934
  5. The DNA sequence of the H-2kb gene: evidence for gene conversion as a mechanism for the generation of polymorphism in histocompatibilty antigens.
    EMBO J. 1983;2(3):453-62 PMID: 11894963
  6. Comparison of alloantisera and hybridoma antibody for purification of the H-2Db murine histocompatibility antigen and preliminary molecular characterization of this antigen.
    J Immunol Methods. 1980;37(3-4):287-99 PMID: 7005347
  7. Biochemistry of the gene products from murine MHC mutants.
    Annu Rev Genet. 1980;14:241-77 PMID: 7011174
  8. A pseudogene homologous to mouse transplantation antigens: transplantation antigens are encoded by eight exons that correlate with protein domains.
    Cell. 1981 Sep;25(3):683-92 PMID: 6895187
  9. Influenza virus-specific cytotoxic T cells are restricted by multiple HLA-A3-related self antigens: evidence for recognition of distinct self structures in conjunction with different foreign antigens.
    J Immunol. 1981 Dec;127(6):2231-5 PMID: 6975312
  10. DNA sequence of a gene encoding a BALB/c mouse Ld transplantation antigen.
    Science. 1982 Feb 5;215(4533):679-82 PMID: 7058332
  11. Exon/intron organization and complete nucleotide sequence of an HLA gene.
    Proc Natl Acad Sci U S A. 1982 Feb;79(3):893-7 PMID: 6461010
  12. Major histocompatibility complex-restricted H-Y-specific antibodies and cytotoxic T lymphocytes may recognize different self determinants.
    J Exp Med. 1982 May 1;155(5):1567-72 PMID: 6175722
  13. Clusters of genes encoding mouse transplantation antigens.
    Cell. 1982 Mar;28(3):489-98 PMID: 6280871
  14. Structure and expression of a mouse major histocompatibility antigen gene, H-2Ld.
    Proc Natl Acad Sci U S A. 1982 Mar;79(6):1994-8 PMID: 6952248
  15. Delineation of immunologically and biochemically distinct HLA-A2 antigens.
    J Immunol. 1982 Aug;129(2):730-4 PMID: 6177780
  16. Recognition of conformational determinants on H-2 by cytolytic T lymphocytes.
    Nature. 1982 Jun 10;297(5866):511-3 PMID: 6178030
  17. Secretion of a soluble class I molecule encoded by the Q10 gene of the C57BL/10 mouse.
    EMBO J. 1985 Feb;4(2):369-74 PMID: 4018029
  18. Structure and expression of two porcine genomic clones encoding class I MHC antigens.
    J Immunol. 1985 Sep;135(3):2167-75 PMID: 2991383
  19. Structure of a gene encoding a murine thymus leukemia antigen, and organization of Tla genes in the BALB/c mouse.
    J Exp Med. 1985 Aug 1;162(2):528-45 PMID: 3894562
  20. Gene duplications in the TL region of the mouse major histocompatibility complex.
    EMBO J. 1985 Jun;4(6):1431-4 PMID: 4029119
  21. Stable transfer and restricted expression of a cloned class I gene encoding a secreted transplantation-like antigen.
    Mol Cell Biol. 1985 Jun;5(6):1295-300 PMID: 4033655
  22. Genes of the major histocompatibility complex of the mouse.
    Annu Rev Immunol. 1983;1:529-68 PMID: 6152713
  23. Molecular cloning and DNA sequence analysis of genes encoding cytotoxic T lymphocyte-defined HLA-A3 subtypes: the E1 subtype.
    J Immunol. 1985 Oct;135(4):2835-41 PMID: 2993417
  24. Comparison of the cloned H-2Kbm1 variant gene with the H-2Kb gene shows a cluster of seven nucleotide differences.
    Proc Natl Acad Sci U S A. 1983 Apr;80(7):2007-11 PMID: 6300887
  25. Hybrid H-2 histocompatibility gene products assign domains recognized by alloreactive T cells.
    Proc Natl Acad Sci U S A. 1983 Apr;80(7):2040-3 PMID: 6188160
  26. Crossreactivity between Qa-1 region and H-2K antigens.
    Transplantation. 1983 Apr;35(4):391-3 PMID: 6836711
  27. Allospecific and virus-specific cytolytic T lymphocytes are restricted to the N or C1 domain of H-2 antigens expressed on L cells after DNA-mediated gene transfer.
    Proc Natl Acad Sci U S A. 1983 May;80(9):2709-12 PMID: 6302702
  28. Human class I histocompatibility antigens (HLA-A,B,C). A small proportion only is phosphorylated.
    Biochem J. 1983 Jan 15;210(1):79-87 PMID: 6303316
  29. HLA-A2 and HLA-B7 antigens are phosphorylated in vitro by rous sarcoma virus kinase (pp60v-src) at a tyrosine residue encoded in a highly conserved exon of the intracellular domain.
    Proc Natl Acad Sci U S A. 1983 May;80(10):2894-8 PMID: 6304688
  30. Genetic mapping in the major histocompatibility complex by restriction enzyme site polymorphisms: most mouse class I genes map to the Tla complex.
    Proc Natl Acad Sci U S A. 1983 Jun;80(11):3425-9 PMID: 6304710
  31. Cross-reactivity patterns of influenza-specific cytotoxic T lymphocytes from H-2Kb mutant mice.
    J Immunol. 1983 Jul;131(1):471-4 PMID: 6190923
  32. The thymic differentiation markers T6 and M241 are two unusual MHC class I antigens.
    J Immunol. 1983 Aug;131(2):851-5 PMID: 6190941
  33. Spontaneous H-2 mutants provide evidence that a copy mechanism analogous to gene conversion generates polymorphism in the major histocompatibility complex.
    Proc Natl Acad Sci U S A. 1983 Jan;80(1):242-6 PMID: 6571997
  34. Separation of H-2Dd, H-2Ld, and H-2Rd by two-dimensional gel electrophoresis.
    Immunogenetics. 1983;17(2):215-8 PMID: 6826213
  35. Subtypes of HLA-B27 detected by cytotoxic T lymphocytes and their role in self-recognition.
    Hum Immunol. 1982 Dec;5(4):259-68 PMID: 6186653
  36. The structure of a mutant H-2 gene suggests that the generation of polymorphism in H-2 genes may occur by gene conversion-like events.
    Nature. 1983 Feb 24;301(5902):671-4 PMID: 6828150
  37. Identification of a second class I antigen controlled by the K end of the H-2 complex and its selective cellular expression.
    Proc Natl Acad Sci U S A. 1983 Mar;80(5):1445-8 PMID: 6572399
  38. Biochemical analysis of variant HLA-B27 antigens.
    Hum Immunol. 1983 Feb;6(2):111-7 PMID: 6601098
  39. Effect of cloned interferon-gamma on expression of H-2 and Ia antigens on cell lines of hemopoietic, lymphoid, epithelial, fibroblastic and neuronal origin.
    Eur J Immunol. 1984 Jan;14(1):52-6 PMID: 6420170
  40. Serologic cross-reactivity between Class I MHC molecules and an H-2-linked differentiation antigen as detected by monoclonal antibodies.
    J Exp Med. 1984 Jan 1;159(1):21-40 PMID: 6363595
  41. Construction, expression and recognition of an H-2 molecule lacking its carboxyl terminus.
    Nature. 1984 Feb 2-8;307(5950):432-6 PMID: 6363940
  42. Detection of a secreted form of the murine H-2 class I antigen with an antibody against its predicted carboxyl terminus.
    Proc Natl Acad Sci U S A. 1984 Feb;81(4):1216-20 PMID: 6583704
  43. Functional expression of a mouse H-2Kb gene isolated from non-expressing teratocarcinoma cells.
    EMBO J. 1984 Mar;3(3):597-601 PMID: 6714227
  44. Modulation of class I HLA antigens on HL-60 promyelocytic leukemia cells by serum-free medium: re-induction by gamma-IFN and 1,25-dihydroxyvitamin D3 (calcitriol).
    J Immunol. 1984 May;132(5):2424-8 PMID: 6425403
  45. Domain interactions of H-2 class I antigens alter cytotoxic T-cell recognition sites.
    Nature. 1984 May 17-23;309(5965):279-81 PMID: 6201750
  46. Complete nucleotide sequence of a gene encoding a functional human class I histocompatibility antigen (HLA-CW3).
    EMBO J. 1984 Apr;3(4):879-85 PMID: 6609813
  47. Complete nucleotide sequence of a functional class I HLA gene, HLA-A3: implications for the evolution of HLA genes.
    EMBO J. 1984 Apr;3(4):887-94 PMID: 6609814
  48. Cysteines in the transmembrane region of major histocompatibility complex antigens are fatty acylated via thioester bonds.
    J Biol Chem. 1984 Jun 10;259(11):7230-8 PMID: 6373770
  49. The Qa-1 alloantigens. II. Evidence for the expression of two Qa-1 molecules by the Qa-1d genotype and for cross-reactivity between Qa-1 and H-2K.
    J Immunol. 1983 Mar;130(3):1293-9 PMID: 6822734
  50. Intramolecular organization of Class I H-2 MHC antigens; localization of the alloantigenic determinants and the beta 2 m binding site to different regions of the H-2 Kb glycoprotein.
    J Immunol. 1983 Mar;130(3):1419-25 PMID: 6185585
  51. CTL cross-reactivities reveal shared immunodominant determinants created by structurally homologous regions of MHC class I antigens.
    J Immunol. 1983 Mar;130(3):1439-46 PMID: 6185588
  52. Tissue-specific expression of an unusual H-2 (class I)-related gene.
    Proc Natl Acad Sci U S A. 1982 Aug;79(16):4947-51 PMID: 6956903
  53. Exon shuffling: mapping polymorphic determinants on hybrid mouse transplantation antigens.
    Nature. 1982 Dec 23;300(5894):755-7 PMID: 6184620
  54. Comparative structural analysis of HLA-A2 antigens distinguishable by cytotoxic T lymphocytes: variants M7 and DR1.
    Biochemistry. 1982 Nov 23;21(24):6313-21 PMID: 6983890
  55. Dimethyl sulfoxide induces expression of H-2 antigens on mouse lung carcinoma cells.
    J Immunol. 1985 Apr;134(4):2790-8 PMID: 2982954
  56. Differential expression of H-2Dd and H-2Ld histocompatibility antigens.
    J Exp Med. 1985 Feb 1;161(2):356-65 PMID: 3919140
  57. DNA sequence of the mouse H-2Dd transplantation antigen gene.
    Proc Natl Acad Sci U S A. 1985 Feb;82(4):1175-9 PMID: 3856254
  58. Characterization of a Q subregion gene in the murine major histocompatibility complex.
    Proc Natl Acad Sci U S A. 1985 Mar;82(5):1503-7 PMID: 2983348
  59. Activation of major histocompatibility complex class I mRNA containing an Alu-like repeat in polyoma virus-transformed rat cells.
    Nature. 1985 Apr 4-10;314(6010):457-9 PMID: 2984576
  60. Expression of class I genes in the major histocompatibility complex: identification of eight distinct mRNAs in DBA/2 mouse liver.
    Cell. 1985 Jun;41(2):469-78 PMID: 3838699
  61. Markedly decreased expression of class I histocompatibility antigens, protein, and mRNA in human small-cell lung cancer.
    J Exp Med. 1985 May 1;161(5):1135-51 PMID: 2580935
  62. Mouse major histocompatibility class I gene expression begins at midsomite stage and is inducible in earlier-stage embryos by interferon.
    Proc Natl Acad Sci U S A. 1985 Apr;82(8):2427-31 PMID: 2581247
  63. Molecular analysis of an EL4 cell line that expresses H-2Db but not H-2Kb or beta 2-microglobulin.
    Proc Natl Acad Sci U S A. 1985 May;82(9):2950-4 PMID: 3887412
  64. The HLA-AW24 gene: sequence, surroundings and comparison with the HLA-A2 and HLA-A3 genes.
    Immunogenetics. 1985;21(5):479-89 PMID: 2987115
  65. Abrogation of metastatic properties of tumour cells by de novo expression of H-2K antigens following H-2 gene transfection.
    Nature. 1985 May 23-29;315(6017):301-5 PMID: 3873616
  66. An adenovirus type 2 glycoprotein blocks cell surface expression of human histocompatibility class I antigens.
    Cell. 1985 Jul;41(3):987-97 PMID: 3924414
  67. Asymmetry in the recognition of HLA-A3 molecules by virus-specific cytotoxic T cells.
    Cell Immunol. 1985 Jul;93(2):497-507 PMID: 2988798
  68. Mouse histocompatibility-related genes are not conserved in other mammals.
    EMBO J. 1985 Mar;4(3):749-53 PMID: 4006905
  69. Functional analysis of the mouse H-2Kb gene promoter in embryonal carcinoma cells.
    Immunogenetics. 1985;21(6):601-11 PMID: 2989166
  70. Structural definition of a family of Ld-like molecules distributed among four of seven haplotypes compared.
    J Immunol. 1985 Aug;135(2):1271-5 PMID: 3925005
  71. A directional process of gene conversion is expected to yield dynamic polymorphism associated with stability of alternative alleles in class I histocompatibility antigens gene family.
    Biochimie. 1983 Apr-May;65(4-5):229-37 PMID: 6409157
  72. Structure of class I major histocompatibility antigens.
    Contemp Top Mol Immunol. 1983;9:1-63 PMID: 6191921
  73. Biochemical isolation of Qa-2 molecules expressed on Qa-2+ leukemias arising in Qa-2- mice.
    Immunogenetics. 1983;18(2):155-7 PMID: 6885119
  74. Transformation of murine LMTK- cells with purified HLA class I genes. III. Human HLA class I antigens coded by hybrid genes constructed in vitro indicate association of serologic reactivities with the first two domains of the molecule.
    Immunogenetics. 1983;18(2):165-71 PMID: 6885121
  75. Clonal analysis of H-2Kb + TNP recognition by T cells with the use of H-2Kbm mutants and H-2Kb-specific monoclonal antibodies.
    J Immunol. 1983 Sep;131(3):1073-9 PMID: 6193173
  76. One (H-2D2b) of the three Db region-controlled molecules (H-2D1b, H-2D2b, H-2Lb) is not detected in bm13 mutant.
    J Immunol. 1983 Sep;131(3):1080-4 PMID: 6604086
  77. Epstein-Barr virus-specific cytotoxic T lymphocytes as probes of HLA polymorphism. Heterogeneity of T cell-restricting determinants associated with the serologically defined HLA-A2 antigen.
    J Exp Med. 1983 Aug 1;158(2):280-93 PMID: 6193217
  78. Expression of the thymus leukemia antigen by activated peripheral T lymphocytes.
    J Exp Med. 1983 Sep 1;158(3):1012-7 PMID: 6604125
  79. Expression and function of transplantation antigens with altered or deleted cytoplasmic domains.
    Cell. 1983 Sep;34(2):535-44 PMID: 6604582
  80. Altered transcription of genes coding for class I histocompatibility antigens in murine tumor cells.
    J Exp Med. 1983 Oct 1;158(4):1294-306 PMID: 6311935
  81. Direct demonstration that cytotoxic T lymphocytes recognize conformational determinants and not primary amino acid sequences.
    J Exp Med. 1983 Nov 1;158(5):1720-6 PMID: 6195291
  82. Expression of class I major histocompatibility antigens switched off by highly oncogenic adenovirus 12 in transformed rat cells.
    Nature. 1983 Oct 27-Nov 2;305(5937):771-5 PMID: 6355856
  83. Tumorigenicity of cells transformed by adenovirus type 12 by evasion of T-cell immunity.
    Nature. 1983 Oct 27-Nov 2;305(5937):776-9 PMID: 6605479
  84. Comparison of class I (H-2) gene sequences. Derivation of unique probes for members of this multigene family.
    J Biol Chem. 1983 Nov 25;258(22):13929-36 PMID: 6315713
  85. Alternative RNA splicing in expression of the H-2K gene.
    Nature. 1983 Dec 8-14;306(5943):602-4 PMID: 6689056
  86. Developmental activation of the H-2K gene is correlated with an increase in DNA methylation.
    Cell. 1983 Dec;35(2 Pt 1):457-65 PMID: 6197180
  87. Aggressiveness of SJL/J lymphomas correlates with absence of H-2Ds antigens.
    J Immunol. 1984 Feb;132(2):945-52 PMID: 6606680
  88. Activation of a Qa/Tla class I major histocompatibility antigen gene is a general feature of oncogenesis in the mouse.
    Nature. 1983 Dec 22-1984 Jan 4;306(5945):756-60 PMID: 6318117
  89. A potential donor gene for the bm1 gene conversion event in the C57BL mouse.
    Nature. 1983 Dec 22-1984 Jan 4;306(5945):792-5 PMID: 6656881
  90. A nonpolymorphic class I gene in the murine major histocompatibility complex.
    Cell. 1984 Jan;36(1):139-44 PMID: 6420070
  91. Identification of several functional subgroups of HLA-B27 by restriction of the activity of antiviral T killer lymphocytes.
    Immunogenetics. 1984;20(5):513-25 PMID: 6094341
  92. Comparative structural analysis of HLA-A3 antigens distinguishable by cytotoxic T lymphocytes: variant E1.
    J Immunol. 1985 Jan;134(1):410-6 PMID: 3871112
  93. Interaction of monoclonal antibodies with MHC class I antigens on mouse spleen cells. II. Levels of expression of H-2K, H-2D, and H-2L in different mouse strains.
    J Immunol. 1985 Jan;134(1):431-5 PMID: 2578048
  94. In vitro mutagenesis of a mouse MHC class I gene for the examination of structure-function relationships.
    J Immunol. 1985 Jan;134(1):623-9 PMID: 3964822
  95. Role of a disulfide bridge in the immune function of major histocompatibility class I antigen as studied by in vitro mutagenesis.
    Proc Natl Acad Sci U S A. 1984 Dec;81(23):7544-8 PMID: 6334311
  96. Functional insertion of an Alu type 2 (B2 SINE) repetitive sequence in murine class I genes.
    Science. 1984 Nov 23;226(4677):974-7 PMID: 6095445
  97. Complete nucleotide sequence of the murine H-2Kk gene. Comparison of three H-2K locus alleles.
    Nucleic Acids Res. 1984 Dec 21;12(24):9473-87 PMID: 6096831
  98. Tracts of high or low sequence divergence in the mouse major histocompatibility complex.
    EMBO J. 1984 Dec 1;3(12):2995-3003 PMID: 6098460
  99. Cloning and complete sequence of an HLA-A2 gene: analysis of two HLA-A alleles at the nucleotide level.
    J Immunol. 1985 Apr;134(4):2727-33 PMID: 2982951
  100. Recognition of H-2Kb mutant target cells by Moloney virus-specific cytotoxic T lymphocytes from bm13 (H-2Db mutant) mice. I. Full recognition of Kbm11 by Kb-restricted CTL.
    J Immunol. 1984 Jul;133(1):24-7 PMID: 6202782
  101. Recognition of H-2Kb mutant target cells by Moloney virus-specific cytotoxic T lymphocytes from bm13 (H-2Db-mutant) mice. II. Relationship of Kbm3 and Kbm11 in restriction specificities and allodeterminants.
    J Immunol. 1984 Jul;133(1):28-32 PMID: 6202783
  102. Biology of cloned cytotoxic T lymphocytes specific for lymphocytic choriomeningitis virus. I. Generation and recognition of virus strains and H-2b mutants.
    J Immunol. 1984 Jul;133(1):433-9 PMID: 6202788
  103. Sexual preference of apparent gene conversion events in MHC genes of mice.
    Nature. 1984 Jun 14-20;309(5969):639-40 PMID: 6728023
  104. Autogenous production of interferon-beta switches on HLA genes during differentiation of histiocytic lymphoma U937 cells.
    EMBO J. 1984 May;3(5):969-73 PMID: 6376119
  105. Structural analysis of an HLA-B7 antigen variant detected by cytotoxic T lymphocytes.
    J Immunol. 1984 Aug;133(2):816-21 PMID: 6429245
  106. Human and murine class I MHC antigens share conserved serine 335, the site of HLA phosphorylation in vivo.
    J Biol Chem. 1984 Jul 25;259(14):9235-40 PMID: 6430898
  107. Molecular characterization of HLA-A28*, a novel HLA product, and its relationship to HLA-A28 and HLA-A2.
    Immunogenetics. 1984;20(2):103-15 PMID: 6332065
  108. Cytotoxic T lymphocytes recognize determinants on the BALB/c-H-2Ld molecule controlled by alpha 1 and alpha 2 but not alpha 3 external domains.
    Immunogenetics. 1984;20(2):141-54 PMID: 6205987
  109. Serological and immunochemical analysis of H-2 class I molecules encoded by the Db region.
    Immunogenetics. 1984;20(3):341-5 PMID: 6469291
  110. A cytolytic human T lymphocyte clone differentially recognizing HLA-B27 subtypes.
    Hum Immunol. 1984 Aug;10(4):237-49 PMID: 6206036
  111. Transcriptional control of HLA-A,B,C antigen in human placental cytotrophoblast isolated using trophoblast- and HLA-specific monoclonal antibodies and the fluorescence-activated cell sorter.
    J Exp Med. 1984 Sep 1;160(3):633-51 PMID: 6206184
  112. Isolation of HLA locus-specific DNA probes from the 3'-untranslated region.
    Proc Natl Acad Sci U S A. 1984 Aug;81(16):5175-8 PMID: 6591185
Article Info
Journal
Immunology
Abbr.
Immunology
ISSN
0019-2805
Published
1986-01-00
Pages
3-18
Language
English
Region
England
NLM ID
0374672
PMCID
PMC1453879
Subset
IM
External Links
PubMed source PMC Full Text View journal details
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