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PMID: 2425338 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Chemical synthesis of branched RNA.

Nucleic acids research ·Vol. 14 ·No. 12 ·1986-06-25 ·Pages 4751-64

Kierzek R, Kopp DW, Edmonds M, Caruthers MH

Abstract

A branched tetranucleotide consisting of adenosine linked 2' and 5' to guanosine and 3' to cytidine was synthesized from appropriately protected nucleoside phosphoramidites as synthons. The product was characterized enzymatically.

MeSH Terms
Chemical Phenomena Chemistry Oligoribonucleotides/chemical synthesis RNA/chemical synthesis RNA Splicing Spectrum Analysis
Chemicals
Oligoribonucleotides RNA
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Kierzek R
Kopp D W
Edmonds M
Caruthers M H
References (15)
15 references, click to expand
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Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
0305-1048
DOI
10.1093/nar/14.12.4751
Published
1986-06-25
Pages
4751-64
Language
English
Region
England
NLM ID
0411011
PMCID
PMC311489
Subset
IM
Grants
NIGMS NIH HHS · GM25680 · United States
NIGMS NIH HHS · GM32585 · United States
External Links
PubMed source DOI: 10.1093/nar/14.12.4751 PMC Full Text View journal details
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