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PMID: 2468999 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Novel tyrosine kinase identified by phosphotyrosine antibody screening of cDNA libraries.

Molecular and cellular biology ·Vol. 8 ·No. 12 ·1988-12-00 ·Pages 5541-4

Kornbluth S, Paulson KE, Hanafusa H

Abstract

In an attempt to clone protein tyrosine kinases, antiphosphotyrosine antibodies were used to screen lambda gt11 cDNA expression libraries. By this method, a 2.5-kilobase cDNA encoding a novel tyrosine kinase was isolated from a mouse liver cDNA library. This new gene is most closely related to the receptor tyrosine kinases ret, fms, and kit.

MeSH Terms
Amino Acid Sequence Antibodies Base Sequence DNA/genetics Humans Molecular Sequence Data Phosphotyrosine Protein-Tyrosine Kinases/genetics Sequence Homology, Nucleic Acid Tyrosine/analogs & derivatives,analysis,immunology
Chemicals
Antibodies Phosphotyrosine Tyrosine DNA Protein-Tyrosine Kinases
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Kornbluth S
Rockefeller University, New York, New York 10021-6399.
Paulson K E
Hanafusa H
References (28)
28 references, click to expand
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Article Info
Journal
Molecular and cellular biology
Abbr.
Mol Cell Biol
ISSN
0270-7306
DOI
10.1128/mcb.8.12.5541-5544.1988
Published
1988-12-00
Pages
5541-4
Language
English
Region
United States
NLM ID
8109087
PMCID
PMC365658
Subset
IM
Grants
PHS HHS · A107233 · United States
NCI NIH HHS · CA 44356 · United States
Databases
GENBANK
M23362
External Links
PubMed source DOI: 10.1128/mcb.8.12.5541-5544.1988 PMC Full Text View journal details
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