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PMID: 2470921 Published · ppublish English Journal Article

Detection of pseudorabies virus transcripts in trigeminal ganglia of latently infected swine.

Journal of virology ·Vol. 63 ·No. 7 ·1989-07-00 ·Pages 2908-13

Cheung AK

Abstract

Two pseudorabies virus (PRV) poly(A)+ RNAs, 2.0 and 0.95 kilobases, were detected in the trigeminal ganglia of latently infected pigs. These RNAs were partially colinear at the 3' end. They were located in the BamHI J fragment (0.706 to 0.737 map units), 3' of the PRV immediate-early gene. A potential polyadenylation signal was also identified in BamHI-J. The direction of transcription of the latency-associated RNAs was antiparallel (i.e., opposite in polarity) to that of the PRV immediate-early mRNA.

MeSH Terms
Animals Blotting, Northern Genes, Viral Herpesvirus 1, Suid/genetics,isolation & purification Poly A/genetics,isolation & purification Pseudorabies/microbiology RNA/genetics,isolation & purification RNA, Messenger/genetics,isolation & purification RNA, Viral/genetics,isolation & purification Restriction Mapping Swine Transcription, Genetic Trigeminal Ganglion/microbiology Trigeminal Nerve/microbiology
Chemicals
RNA, Messenger RNA, Viral Poly A RNA
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Cheung A K
National Animal Disease Center, Agricultural Research Service, U.S. Department of Agriculture, Ames, Iowa 50010.
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30 references, click to expand
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Article Info
Journal
Journal of virology
Abbr.
J Virol
ISSN
0022-538X
DOI
10.1128/JVI.63.7.2908-2913.1989
Published
1989-07-00
Pages
2908-13
Language
English
Region
United States
NLM ID
0113724
PMCID
PMC250841
Subset
IM
External Links
PubMed source DOI: 10.1128/JVI.63.7.2908-2913.1989 PMC Full Text View journal details
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